Evidence map›Paper›PMID 33050154›Full record

ArticleMolecules (Basel, Switzerland)2020

Loseolamycins: A Group of New Bioactive Alkylresorcinols Produced after Heterologous Expression of a Type III PKS from

Constanze Lasch, Nils Gummerlich, Maksym Myronovskyi, Anja Palusczak, Josef Zapp, Andriy Luzhetskyy

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Synthetic and systems biotechnology · 2026
    Review
  2. Antimicrobial Activity of Actinobacteria Isolated From Kratom (International journal of microbiology · 2026
    Article
  3. New Marine Actinobacteria Strain,Microorganisms · 2025
    Article
  4. Taxonomic description ofMicrobiology spectrum · 2025
    Article
  5. Article
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  8. Article
  9. Article
  10. Review
  11. Bacterial natural product discovery by heterologous expression.Journal of industrial microbiology & biotechnology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Constanze LaschPharmaceutical Biotechnology, Saarland University, 66123 Saarbruecken, Germany.
Nils GummerlichPharmaceutical Biotechnology, Saarland University, 66123 Saarbruecken, Germany.
Maksym MyronovskyiPharmaceutical Biotechnology, Saarland University, 66123 Saarbruecken, Germany.
Anja PalusczakPharmaceutical Biotechnology, Saarland University, 66123 Saarbruecken, Germany.
Josef ZappPharmaceutical Biology, Saarland University, 66123 Saarbruecken, Germany.
Andriy LuzhetskyyPharmaceutical Biotechnology, Saarland University, 66123 Saarbruecken, Germany.
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural products are a valuable source of biologically active compounds with potential applications in medicine and agriculture. Unprecedented scaffold diversity of natural products and biocatalysts from their biosynthetic pathways are of fundamental importance. Heterologous expression and refactoring of natural product biosynthetic pathways are generally regarded as a promising approach to discover new secondary metabolites of microbial origin. Here, we present the identification of a new group of alkylresorcinols after transcriptional activation and heterologous expression of the type III polyketide synthase of

Indexed as

Gene Expression Regulation, BacterialMagnetic Resonance SpectroscopyMicromonosporaPolyketide SynthasesStreptomycesPolyketide Synthasesalkylresorcinolbiosynthetic geneheterologous expressionMicromonospora endolithicaStreptomyces albus Del14type III polyketide synthase

Identifiers

PMID33050154
PMCPMC7587189
OpenAlexW3091791661

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.