Evidence map›Paper›PMID 33050082›Full record

ArticleToxins2020

Cross-Reactive Carbohydrate Determinant in

Débora Moitinho Abram, Luís Gustavo Romani Fernandes, Amilcar Perez-Riverol, Márcia Regina Brochetto-Braga, Ricardo de Lima Zollner

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Débora Moitinho AbramLaboratory of Translational Immunology, Medicine School, FCM, University of Campinas (UNICAMP), Rua Tessália Vieira de Camargo, nº 126, 13083-888, Cidade Universitária "Zeferino Vaz", Campinas SP 13500, Brazil.
Luís Gustavo Romani FernandesLaboratory of Translational Immunology, Medicine School, FCM, University of Campinas (UNICAMP), Rua Tessália Vieira de Camargo, nº 126, 13083-888, Cidade Universitária "Zeferino Vaz", Campinas SP 13500, Brazil.
Amilcar Perez-RiverolCenter for the Study of Social Insects, Department of General and Applied Biology, Institute of Biosciences of Rio Claro, Institute of Biosciences of Rio Claro, São Paulo State University, Rio Claro SP 13500, Brazil.
Márcia Regina Brochetto-BragaCenter for the Study of Social Insects, Department of General and Applied Biology, Institute of Biosciences of Rio Claro, Institute of Biosciences of Rio Claro, São Paulo State University, Rio Claro SP 13500, Brazil.ORCID 0000-0002-7982-0743
Ricardo de Lima ZollnerLaboratory of Translational Immunology, Medicine School, FCM, University of Campinas (UNICAMP), Rua Tessália Vieira de Camargo, nº 126, 13083-888, Cidade Universitária "Zeferino Vaz", Campinas SP 13500, Brazil.ORCID 0000-0002-1639-2841
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

CAPES 02P-4636-2019Conselho Nacional de Desenvolvimento Científico e Tecnológico 455422/2014-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/00729-7
6 · The paper itself

Abstract

Allergic reactions to Hymenoptera venom, which could lead to systemic and even fatal symptoms, is characterized by hypersensitivity reactions mediated by specific IgE (sIgE) driven to venom allergens. Patients multisensitized to sIgE usually recognize more than one allergen in different Hymenoptera species. However, the presence of sIgE directed against Cross-Reactive Carbohydrate Determinant (CCD), which occurs in some allergens from Hymenoptera venom, hampers the identification of the culprit insects. CCD is also present in plants, pollen, fruits, but not in mammals. Bromelain (Brl) extracted from pineapples is a glycoprotein commonly used for reference to sIgE-CCD detection and analysis. In sera of fifty-one Hymenoptera allergic patients with specific IgE ≥ 1.0 KU/L, we assessed by immunoblotting the reactivity of sIgE to the major allergens of

Indexed as

AdolescentAdultAllergensAntibody SpecificityAnt VenomsBee VenomsBromelainsCarbohydratesChildChild, PreschoolCross ReactionsEpitopesFemaleHumansHypersensitivityImmunoglobulin EAllergensAnt VenomsBee VenomsBromelainsCarbohydratesEpitopesImmunoglobulin EWasp Venomsbromelaincross-reactive carbohydrateHymenoptera venom allergyKeywordsPolybia paulista

Identifiers

PMID33050082
PMCPMC7599856
OpenAlexW3091904078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.