Evidence map›Paper›PMID 33050033›Full record

ArticlePathogens (Basel, Switzerland)2020

Bacterial Lipoteichoic Acid Attenuates Toll-Like Receptor Dependent Dendritic Cells Activation and Inflammatory Response.

Suguru Saito, Alato Okuno, Duo-Yao Cao, Zhenzi Peng, Hui-Ya Wu, Shu-Hui Lin

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
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  4. Differential expression ofVeterinary world · 2025
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  7. The Regulatory Effect of Coaggregation BetweenFrontiers in cellular and infection microbiology · 2022
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Suguru SaitoBio-fluid Biomarker Center, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 9502181, Japan.
Alato OkunoDepartment of Health and Nutrition, Tsukuba international university, Ibaraki 3000051, Japan.
Duo-Yao CaoCollege of Animal Science and Technology, Northwest A&F University, Shaanxi 712100, China.
Zhenzi PengDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Hui-Ya WuCollege of Health Science, Trans World University, Douliu 64063, Taiwan.
Shu-Hui LinMedical Science International, Taipei 115, Taiwan.
Cedars-Sinai Medical Center · USIbaraki University · JPTransWorld University · TWXiangya Hospital Central South University · CN

Funding

Japan Agency for Medical Research and Development 17fk0210305h0003Japan Society for the Promotion of Science 16H06814
6 · The paper itself

Abstract

Toll-like receptor (TLR) signaling is an indispensable factor in immune cells activation. Many TLR ligands have been identified, and were characterized the immunological functions such as inflammatory cytokine production in immune cells. However, the anti-inflammatory response in TLR ligand-mediated manner is poorly understood. In this report, we show that bacterial lipoteichoic acid (LTA), which is a TLR2 ligand from gram-positive bacteria including

Indexed as

acute skin inflammationdendritic cell (DCs)effector CD4+ T cellsimmunosuppressivelipoteichoic acid (LTA)Staphylococcus aureus (S. aureus)toll-like receptor (TLRs)

Identifiers

PMID33050033
PMCPMC7600882
OpenAlexW3092101863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.