Evidence map›Paper›PMID 33050003›Full record

ArticleInternational journal of molecular sciences2020

Serum-Based Proteomics Profiling in Adult Patients with Cystic Fibrosis.

Hicham Benabdelkamel, Hanadi Alamri, Meshail Okla, Afshan Masood, Mai Abdel Jabar, Ibrahim O Alanazi, Assim A Alfadda, Imran Nizami, Majed Dasouki, Anas M Abdel Rahman

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
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  11. Biomarkers in Rare Diseases.International journal of molecular sciences · 2021
    Article
  12. Distinctive metabolic profiles between Cystic Fibrosis mutational subclasses and lung function.Metabolomics : Official journal of the Metabolomic Society · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Hicham BenabdelkamelProteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, PO. Box 2925 (98), Riyadh 11461, Saudi Arabia.
Hanadi AlamriDepartment of Biochemistry and Molecular Medicine,College of Medicine, Al Faisal University, Riyadh 11461, Saudi Arabia.
Meshail OklaDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, 183T11, Riyadh 11495, Saudi Arabia.ORCID 0000-0003-4855-243X
Afshan MasoodProteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, PO. Box 2925 (98), Riyadh 11461, Saudi Arabia.ORCID 0000-0001-8082-9326
Mai Abdel JabarDepartment of Genetics, King Faisal Specialist Hospital and Research Centre (KFSHRC), Zahrawi Street, Al Maather, Riyadh 11211, Saudi Arabia.
Ibrahim O AlanaziThe National Center for Biotechnology (NCB), Life Science and Environment Research Institute, King Abdulaziz City for Science and Technology (KACST), PO. Box 6086, Riyadh 11461, Saudi Arabia.
Assim A AlfaddaProteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, PO. Box 2925 (98), Riyadh 11461, Saudi Arabia.ORCID 0000-0002-4792-5188
Imran NizamiLung Transplant Section, Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Zahrawi Street, Al Maather, Riyadh 11211, Saudi Arabia.
Majed DasoukiDepartment of Genetics, King Faisal Specialist Hospital and Research Centre (KFSHRC), Zahrawi Street, Al Maather, Riyadh 11211, Saudi Arabia.
Anas M Abdel RahmanDepartment of Biochemistry and Molecular Medicine,College of Medicine, Al Faisal University, Riyadh 11461, Saudi Arabia.ORCID 0000-0002-9527-9424
King Saud University · SAKing Faisal Specialist Hospital & Research Centre · SAAlfaisal University · SAKing Abdulaziz City for Science and Technology · SAMemorial University of Newfoundland · CA

Funding

King Saud University RGP-334
6 · The paper itself

Abstract

Cystic fibrosis (CF), the most common lethal autosomal recessive disorder among Caucasians, is caused by mutations in the CF transmembrane conductance regulator (CFTR) chloride channel gene. Despite significant advances in the management of CF patients, novel disease-related biomarkers and therapies must be identified. We performed serum proteomics profiling in CF patients (

Indexed as

ProteomeTranscriptomeAdolescentAdultBiomarkersChildCohort StudiesCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorFemaleGene Expression ProfilingHumansMaleMutationProtein Interaction MapsProteomicsBiomarkersCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorProteomebiomarkerCFTRcystic fibrosisDIGE-MALDI/TOFproteomics

Identifiers

PMID33050003
PMCPMC7582405
OpenAlexW3092603048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.