Evidence map›Paper›PMID 33049985›Full record

ArticleInternational journal of molecular sciences2020

Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington's Disease Status Based on Omics Data.

Christiana C Christodoulou, Margarita Zachariou, Marios Tomazou, Evangelos Karatzas, Christiana A Demetriou, Eleni Zamba-Papanicolaou, George M Spyrou

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 29 citations in OpenAlex.

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  9. Biomarkers in medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Christiana C ChristodoulouBioinformatics Department; Cyprus Institute of Neurology and Genetics; Cyprus School of Molecular Medicine, 2371 Nicosia, Cyprus.ORCID 0000-0002-6071-1715
Margarita ZachariouBioinformatics Department; Cyprus Institute of Neurology and Genetics; Cyprus School of Molecular Medicine, 2371 Nicosia, Cyprus.ORCID 0000-0001-8950-4077
Marios TomazouBioinformatics Department; Cyprus Institute of Neurology and Genetics; Cyprus School of Molecular Medicine, 2371 Nicosia, Cyprus.ORCID 0000-0002-0836-5579
Evangelos KaratzasDepartment of Informatics and Telecommunications, University of Athens, 157 72 Athens, Greece.
Christiana A DemetriouDepartment of Primary Care and Population Health, University of Nicosia, 2417 Nicosia, Cyprus.
Eleni Zamba-PapanicolaouNeurology Clinic D; Cyprus Institute of Neurology and Genetics; Cyprus School of Molecular Medicine, 2371 Nicosia, Cyprus.
George M SpyrouBioinformatics Department; Cyprus Institute of Neurology and Genetics; Cyprus School of Molecular Medicine, 2371 Nicosia, Cyprus.ORCID 0000-0002-2470-3363
Cyprus Institute of Neurology and Genetics · CYNational and Kapodistrian University of Athens · GRUniversity of Nicosia · CY

Funding

This research was funded by the European Commission Research Executive Agency (REA) Grant BIORISE, under the Spreading Excellence, Widening Participation Science with and for Society Framework. 669026
6 · The paper itself

Abstract

Huntington's disease is a rare neurodegenerative disease caused by a cytosine-adenine-guanine (CAG) trinucleotide expansion in the Huntingtin (

Indexed as

Asymptomatic DiseasesGene Expression RegulationGene Regulatory NetworksMetabolomeComputational BiologyDatabases, GeneticFemaleGene ExpressionHumansHuntington DiseaseMaleMetabolomicsSignal Transductiondifferentially expressed genesgene co-expressionhuntington’s diseasemetabolitesnetwork biologynetwork rewiringpathwayssystems bioinformatics

Identifiers

PMID33049985
PMCPMC7582902
OpenAlexW3092604457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.