Evidence map›Paper›PMID 33049910›Full record

ArticleCancers2020

Genomic Instability Signature of Palindromic Non-Coding Somatic Mutations in Bladder Cancer.

Sophie Vacher, Voreak Suybeng, Elodie Girard, Julien Masliah Planchon, Grégory Thomson, Constance Le Goux, Simon Garinet, Anne Schnitzler, Walid Chemlali, Virginie Firlej and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Current issues in molecular biology · 2025
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  4. Review
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  9. The Role of Emerin in Cancer Progression and Metastasis.International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Sophie VacherUnité de Pharmacogénomique, Service de Génétique, Institut Curie, F-75005 Paris, France.ORCID 0000-0002-0042-6023
Voreak SuybengUnité de Pharmacogénomique, Service de Génétique, Institut Curie, F-75005 Paris, France.
Elodie GirardPlateforme de Bioinformatique, Centre de Recherche de l'Institut Curie, F-75005 Paris, France.
Julien Masliah PlanchonUnité de Génétique Somatique, Service de Génétique, Institut Curie, F-75005 Paris, France.
Grégory ThomsonUnité de Pharmacogénomique, Service de Génétique, Institut Curie, F-75005 Paris, France.
Constance Le GouxUnité de Pharmacogénomique, Service de Génétique, Institut Curie, F-75005 Paris, France.ORCID 0000-0002-8543-4320
Simon GarinetUnité de Pharmacogénomique, Service de Génétique, Institut Curie, F-75005 Paris, France.
Anne SchnitzlerUnité de Pharmacogénomique, Service de Génétique, Institut Curie, F-75005 Paris, France.
Walid ChemlaliUnité de Pharmacogénomique, Service de Génétique, Institut Curie, F-75005 Paris, France.
Virginie FirlejTRePCa, Université Paris Est Créteil, F-94010 Créteil, France.ORCID 0000-0003-4132-0695
Diane DamotteService d'Anatomopathologie, Hôpital Cochin, F-75014 Paris, France.
Yves AlloryDépartement de Pathologie, Institut Curie, F-92210 Saint-Cloud, France.
Maud KamalInstitut Curie, Department of Drug Development and Innovation (D3i), Institut Curie Paris & Saint Cloud, F-75005 Paris, France.
Géraldine PignotDépartement d'Urologie, Unité de Chirurgie Oncologique, Institut Paoli-Calmettes, F-13009 Marseille, France.
Ivan BiecheUnité de Pharmacogénomique, Service de Génétique, Institut Curie, F-75005 Paris, France.
Institut Curie · FRInserm · FRDélégation Paris 5 · FRInstitut Pprime · FRUniversité Paris-Est Créteil · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous pan-genomic studies identified alterations in protein-coding genes and signaling pathways involved in bladder carcinogenesis, while non-coding somatic alterations remain weakly explored. The goal of this study was to identify clinical biomarkers in non-coding regions for bladder cancer patients. We have previously identified in bladder tumors two non-coding mutational hotspots occurring at high frequencies (≥30%). These mutations are located close to the

Indexed as

bladder cancerclinical biomarkersgenomic instability signaturenon-coding mutation

Identifiers

PMID33049910
PMCPMC7650671
OpenAlexW3092044306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.