Evidence map›Paper›PMID 33049167›Full record

ArticleProceedings. Biological sciences2020

Experimental evidence of warming-induced disease emergence and its prediction by a trait-based mechanistic model.

Devin Kirk, Pepijn Luijckx, Natalie Jones, Leila Krichel, Clara Pencer, Péter Molnár, Martin Krkošek

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Infection burdens and virulence under heat stress: ecological and evolutionary considerations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  11. Temperature modifies trait-mediated infection outcomes in aPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Devin KirkDepartment of Ecology and Evolutionary Biology, University of Toronto, Toronto, Canada.
Pepijn LuijckxSchool of Natural Sciences, Zoology Department, Trinity College Dublin, University of Dublin, Dublin, Republic of Ireland.
Natalie JonesSchool of Biological Sciences, University of Queensland, Brisbane, Australia.
Leila KrichelDepartment of Ecology and Evolutionary Biology, University of Toronto, Toronto, Canada.
Clara PencerDepartment of Ecology and Evolutionary Biology, University of Toronto, Toronto, Canada.
Péter MolnárDepartment of Ecology and Evolutionary Biology, University of Toronto, Toronto, Canada.
Martin KrkošekDepartment of Ecology and Evolutionary Biology, University of Toronto, Toronto, Canada.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Predicting the effects of seasonality and climate change on the emergence and spread of infectious disease remains difficult, in part because of poorly understood connections between warming and the mechanisms driving disease. Trait-based mechanistic models combined with thermal performance curves arising from the metabolic theory of ecology (MTE) have been highlighted as a promising approach going forward; however, this framework has not been tested under controlled experimental conditions that isolate the role of gradual temporal warming on disease dynamics and emergence. Here, we provide experimental evidence that a slowly warming host-parasite system can be pushed through a critical transition into an epidemic state. We then show that a trait-based mechanistic model with MTE functional forms can predict the critical temperature for disease emergence, subsequent disease dynamics through time and final infection prevalence in an experimentally warmed system of

Indexed as

Climate ChangeHost-Parasite InteractionsParasitesAnimalsDaphniaEcologyEpidemicsMicrosporidiaTemperatureDaphnia magnametabolic theory of ecologyOrdospora colligataparasitetemperaturethermal ecology

Identifiers

PMID33049167
PMCPMC7657857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.