ArticlePLoS genetics2020
Chromosome number evolves at equal rates in holocentric and monocentric clades.
Article in PLoS genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- A haplotype-resolved nutmeg genome reveals XY sex chromosome evolution and enables molecular sexing.Communications biology · 2026Article
- Dismantling Chromosomal Stasis Across the Eukaryotic Tree of Life.bioRxiv : the preprint server for biology · 2026Article
- Rapid genome modifications including chromosomal fusions and large-scale inversions are key features in Arctic codfish species.Genome biology · 2026Article
- Genome Architecture and Speciation in Plants and Animals.Molecular ecology · 2025Review
- A comparative genomic analysis at the chromosomal-level reveals evolutionary patterns of aphid chromosomes.Communications biology · 2025Article
- Neo-Sex Chromosome Evolution in Treehoppers Despite Long-Term X Chromosome Conservation.Genome biology and evolution · 2024Article
- Genome report: Genome sequence of tuliptree scale, Toumeyella liriodendri (Gmelin), an ornamental pest insect.G3 (Bethesda, Md.) · 2024Article
- Drift drives the evolution of chromosome number II: The impact of range size on genome evolution in Carnivora.The Journal of heredity · 2024Article
- A macroevolutionary role for chromosomal fusion and fission inScience advances · 2024Article
- Comparative genomics reveals the dynamics of chromosome evolution in Lepidoptera.Nature ecology & evolution · 2024Article
- Drift drives the evolution of chromosome number I: The impact of trait transitions on genome evolution in Coleoptera.The Journal of heredity · 2024Article
- Phylloxera and Aphids Show Distinct Features of Genome Evolution Despite Similar Reproductive Modes.Molecular biology and evolution · 2023Article
- The Impact of Chromosomal Rearrangements in Speciation: From Micro- to Macroevolution.Cold Spring Harbor perspectives in biology · 2023Review
- Whole-Genome Analysis Reveals the Dynamic Evolution of Holocentric Chromosomes in Satyrine Butterflies.Genes · 2023Article
- Article
- High-density linkage maps and chromosome level genome assemblies unveil direction and frequency of extensive structural rearrangements in wood white butterflies (Leptidea spp.).Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023Article
- Evolution of sexual systems, sex chromosomes and sex-linked gene transcription in flatworms and roundworms.Nature communications · 2022Article
- Dissecting cricket genomes for the advancement of entomology and entomophagy.Biophysical reviews · 2022Review
- Diptera andFrontiers in ecology and evolution · 2022Article
- Comparative analysis of chromosome numbers and sex chromosome systems in Paraneoptera (Insecta).Comparative cytogenetics · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Despite the fundamental role of centromeres two different types are observed across plants and animals. Monocentric chromosomes possess a single region that function as the centromere while in holocentric chromosomes centromere activity is spread across the entire chromosome. Proper segregation may fail in species with monocentric chromosomes after a fusion or fission, which may lead to chromosomes with no centromere or multiple centromeres. In contrast, species with holocentric chromosomes should still be able to safely segregate chromosomes after fusion or fission. This along with the observation of high chromosome number in some holocentric clades has led to the hypothesis that holocentricity leads to higher rates of chromosome number evolution. To test for differences in rates of chromosome number evolution between these systems, we analyzed data from 4,393 species of insects in a phylogenetic framework. We found that insect orders exhibit striking differences in rates of fissions, fusions, and polyploidy. However, across all insects we found no evidence that holocentric clades have higher rates of fissions, fusions, or polyploidy than monocentric clades. Our results suggest that holocentricity alone does not lead to higher rates of chromosome number changes. Instead, we suggest that other co-evolving traits must explain striking differences between clades.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.