Evidence map›Paper›PMID 33048937›Full record

ArticlePloS one2020

Epidemiological study of prevalent pathogens in the Northwest region of Argentina (NWA).

Mónica Florencia Torrez Lamberti, Fabián Enrique López, Patricia Valdez, Ana Bianchi, Evangelina Barrionuevo Medina, María de Las Mercedes Pescaretti, Mónica Alejandra Delgado

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mónica Florencia Torrez LambertiInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT, San Miguel de Tucumán, Argentina.
Fabián Enrique LópezInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT, San Miguel de Tucumán, Argentina.
Patricia ValdezHospital Interzonal de Niños Eva Perón (HINEP), San Fernando del Valle de Catamarca, Catamarca, Argentina.
Ana BianchiCentro Provincial de Salud Infantil "Eva Perón" (CePSI), Santiago del Estero, Argentina.
Evangelina Barrionuevo MedinaHospital del Niño Jesús (HNJ), San Miguel de Tucumán, Tucumán, Argentina.
María de Las Mercedes PescarettiInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT, San Miguel de Tucumán, Argentina.
Mónica Alejandra DelgadoInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT, San Miguel de Tucumán, Argentina.ORCID 0000-0002-4283-6979

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Northwest Argentina (NWA) is a poor economic-geographical region, with the highest rate of diarrhea diseases. At the moment, there are no reports showing the epidemiological status of this region that would allow to establish methods for prevention and control of these infections and to indicate of the prevalent pathogen that produces them. Therefore we carried out an epidemiological study of the gastroenteritis etiological agents and their incidence in the pediatric population. A total of 17 823 fecal samples were collected, 14 242 from HNJ-Tuc, 2,257 from CePSI-Stgo and 1,324 from HINEP-Cat. In 2,595 samples a bacterial agent was identified, the 93.64% corresponded to Shigella/Salmonella clinical isolates. Shigella genus was the prevalent pathogen, being Shigella flexneri 2 the most frequent serotype. Most of the Shigella clinical isolates presented themselves as multidrug-resistant (MDR), harboring 2 to 3 genetic resistance determinants. 50% of the affected patients were children under 4 years old. Here, we demonstrate that bacterial gastrointestinal diseases strongly affect the health of NWA population. The appearance of epidemic outbreaks, as happened during 2014, suggest that they may be related to the socio-economic poverty of NWA. Recently, Shigella flexneri 2 has become the highest NWA´s incidence infectious agent. The acquisition of new antibiotic resistance determinants may play an important role in their adaptation and persistence.

Indexed as

AdolescentArgentinaBacterial InfectionsChildChild, PreschoolDiarrheaDrug Resistance, Multiple, BacterialDysentery, BacillaryEpidemiologic StudiesFecesFemaleHumansInfantInfant, NewbornMaleMultiplex Polymerase Chain Reaction

Identifiers

PMID33048937
PMCPMC7553278

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.