ArticleCritical care medicine2020
A Core Outcome Set for Pediatric Critical Care.
Article in Critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Ketamine for Analgosedation in Critically Ill Mechanically Ventilated Children: A Systematic Review and Meta-Analysis.Critical care explorations · 2026Pooled it
- Identifying outcomes and outcome measures in neonatal family-centered care trials: a systematic review.Pediatric research · 2025Pooled it
- Synthesizing Core Outcome Sets for outcomes research in cohort studies: a systematic review.Pediatric research · 2022Pooled it
- Comparison of a Cardiac Specific Versus a General Instrument to Assess Health-Related Quality of Life 4-5 Years After Cardiac Surgery in Early Infancy.CJC pediatric and congenital heart disease · 2026Article
- Review
- Feeding Recovery in Post-PICU Patients: A Case Series in an Intensive Feeding Program.Nutrients · 2026Article
- Pediatric Intensive Care Core Outcomes-a modified Delphi consensus process (PIC-CO).Critical care (London, England) · 2026Review
- Feed Modification for Improved Energy and Protein Provision for Infants and Young Children in the Pediatric Critical Care Setting: A Scoping Review.Nutrition reviews · 2025Article
- Eight PICU Follow-Up Programs in the United States Established From 2013 to 2022: Report From the Pediatric Outcomes Studies After PICU (POST-PICU) Investigators.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Pain, Agitation, Delirium, and Iatrogenic Withdrawal Syndrome Management in Children Who Are Critically Ill: Protocol for a European Clinical Practice Guideline Using the Grading of Recommendations Assessment, Development, and Evaluation Approach.JMIR research protocols · 2025Article
- Health-Related Quality of Life in Children 4-5 Years After Open Heart Surgery in Early Infancy.CJC pediatric and congenital heart disease · 2025Article
- Physical Activity Monitoring in Children in the 1-Year After 3 or More Days of Invasive Ventilation: Feasibility of Using Accelerometers.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Hospital to home transition of children with medical complexities in the Netherlands: current practice.European journal of pediatrics · 2025Observational
- Developing an adaptive paediatric intensive care unit platform trial with key stakeholders: a qualitative study.BMJ open · 2025Article
- Efficacy and safety of analgosedation with dexmedetomidine in critically ill mechanically ventilated children: a systematic review and meta-analysis of randomized controlled trials.Intensive care medicine. Paediatric and neonatal · 2025Article
- Validation of the BioIntelliSense BioButton® device for physical activity monitoring in children and future application as a physical health outcome for critically Ill children.Frontiers in pediatrics · 2025Article
- Pediatric Post-Intensive Care Syndrome and Current Therapeutic Options.Critical care clinics · 2025Review
- Post-intensive-care morbidity among pediatric patients in Thailand: prevalence, risk factors, and the importance of the post-intensive-care clinic.Acute and critical care · 2024Article
- Supporting families during pediatric critical illness: Opportunities identified in a multicenter, qualitative study.Journal of child health care : for professionals working with children in the hospital and community · 2024Article
- Establishing a paediatric critical care core quality measure set using a multistakeholder, consensus-driven process.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2024Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
37 authors.
Funding
Abstract
objectivesMore children are surviving critical illness but are at risk of residual or new health conditions. An evidence-informed and stakeholder-recommended core outcome set is lacking for pediatric critical care outcomes. Our objective was to create a multinational, multistakeholder-recommended pediatric critical care core outcome set for inclusion in clinical and research programs.
designA two-round modified Delphi electronic survey was conducted with 333 invited research, clinical, and family/advocate stakeholders. Stakeholders completing the first round were invited to participate in the second. Outcomes scoring greater than 69% "critical" and less than 15% "not important" advanced to round 2 with write-in outcomes considered. The Steering Committee held a virtual consensus conference to determine the final components.
settingMultinational survey. PATIENTS: Stakeholder participants from six continents representing clinicians, researchers, and family/advocates. MEASUREMENTS AND MAIN
resultsOverall response rates were 75% and 82% for each round. Participants voted on seven Global Domains and 45 Specific Outcomes in round 1, and six Global Domains and 30 Specific Outcomes in round 2. Using overall (three stakeholder groups combined) results, consensus was defined as outcomes scoring greater than 90% "critical" and less than 15% "not important" and were included in the final PICU core outcome set: four Global Domains (Cognitive, Emotional, Physical, and Overall Health) and four Specific Outcomes (Child Health-Related Quality of Life, Pain, Survival, and Communication). Families (n = 21) suggested additional critically important outcomes that did not meet consensus, which were included in the PICU core outcome set-extended.
conclusionsThe PICU core outcome set and PICU core outcome set-extended are multistakeholder-recommended resources for clinical and research programs that seek to improve outcomes for children with critical illness and their families.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.