Evidence map›Paper›PMID 33048884›Full record

ArticleAIDS (London, England)2020

Ending an HIV epidemic among persons who inject drugs in a middle-income country: extremely low HIV incidence among persons who inject drugs in Hai Phong, Viet Nam.

Don C Des Jarlais, Duong Thi Huong, Khuat Thi Hai Oanh, Jonathan P Feelemyer, Kamyar Arasteh, Pham Minh Khue, Hoang Thi Giang, Nham Thi Tuyet Thanh, Vu Hai Vinh, Sao Mai Le and 8 more

Open access · greenAbstract read
In one paragraph

Article in AIDS (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Perspectives on addiction-related problems in Vietnam.Addiction (Abingdon, England) · 2026
    Review
  5. Article
  6. Article
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  8. High prevalence and incidence of HSV-2 among people who inject drugs in Hai Phong, Vietnam, and risk factors associated with seroconversion.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
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  14. Availability of HIV surveillance data in key populations in the countries of the World Health Organization Eastern Mediterranean Region.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 4 countries.

Don C Des JarlaisNew York University School of Global Public Health, New York, New York, USA.
Duong Thi HuongHaiphong University of Medicine and Pharmacy, Haiphong.
Khuat Thi Hai OanhSupporting Community Development Initiatives, Hanoi.
Jonathan P FeelemyerNew York University School of Global Public Health, New York, New York, USA.
Kamyar ArastehNew York University School of Global Public Health, New York, New York, USA.
Pham Minh KhueHaiphong University of Medicine and Pharmacy, Haiphong.
Hoang Thi GiangHaiphong University of Medicine and Pharmacy, Haiphong.
Nham Thi Tuyet ThanhSupporting Community Development Initiatives, Hanoi.
Vu Hai VinhDepartment of Infectious and Tropical Diseases, Viet Tiep Hospital, Haiphong, Vietnam.
Sao Mai LeHaiphong University of Medicine and Pharmacy, Haiphong.
Roselyne ValloPathogenèses and Control of Chronic Infections, Inserm, Etablissement Français du Sang, University of Montpellier, Montpellier.
Catherine QuilletPathogenèses and Control of Chronic Infections, Inserm, Etablissement Français du Sang, University of Montpellier, Montpellier.
Delphine RapoudPathogenèses and Control of Chronic Infections, Inserm, Etablissement Français du Sang, University of Montpellier, Montpellier.
Laurent MichelPierre Nicole Center, French Red Cross, CESP/Inserrm 1018, Paris.
Didier LaureillardPathogenèses and Control of Chronic Infections, Inserm, Etablissement Français du Sang, University of Montpellier, Montpellier.
Jean Pierre MolesPathogenèses and Control of Chronic Infections, Inserm, Etablissement Français du Sang, University of Montpellier, Montpellier.
Nicolas NagotPathogenèses and Control of Chronic Infections, Inserm, Etablissement Français du Sang, University of Montpellier, Montpellier.
DRIVE Study Team
Établissement Français du Sang · FRNew York University · USDevelopment Initiatives · GBHai Phong University · VNCentre de recherche en Epidémiologie et Santé des Populations · FRHai Phong University of Management and Technology · VNHai phong University Of Medicine and Pharmacy · VNHung Vuong Hospital · VNInserm · FRPathogenesis and Control of Chronic and Emerging Infections

Funding

Risk Factors for HIV/AIDS in Drug UsersR01DA003574 · NIDA · NEW YORK UNIVERSITY · PI DES JARLAIS, DON C, MCKNIGHT, COURTNEY · 1986 to 2025
$16.2M
DRIVE (DRug use and blood-borne Infections in ViEtnam): Combined prevention and care to end the HIV epidemic among people who inject drugs in Haiphong, Viet NamR01DA041978 · NIDA · NEW YORK UNIVERSITY · PI DES JARLAIS, DON C · 2016 to 2020
$4.9M
NIDA NIH HHS R01 DA003574NIDA NIH HHS R01 DA041978
6 · The paper itself

Abstract

objectiveTo determine whether it is possible to 'end an HIV epidemic' among persons who inject drugs (PWID) in a low/middle income country.

designSerial cross-sectional surveys with a cohort of HIV seronegative participants with 6-month follow-up visits recruited from surveys.

methodsSurveys of PWID using respondent driven and snowball sampling were conducted in 2016, 2017, 2018, and 2019 (N = 1383, 1451, 1444, and 1268). HIV recency testing was used to identify possible seroconversions in the window period prior to study entry. Structured interviews covering drug use histories, current drug use, and use of HIV-related services were administered by trained interviewers. Urinalysis was used to confirm current drug use. HIV and hepatitis C virus testing were conducted. Electronic fingerprint readers were used to avoid multiple participation in each survey and to link participants across surveys. A cohort of HIV seronegative participants with 6-month follow-up visits was recruited from the surveys, 480 from 2016, 233 from 2017, and 213 from 2018.

resultsParticipants were predominantly male (95%), mean age approximately 40, all reported injecting heroin, HIV prevalence ranged between 26 and 30%. We had three seroconversions in 1483 person-years at risk (PYAR) in the cohort study, and 0 in 696 PYAR among repeat survey participants, and 0 seroconversions in 1344 PYAR in recency testing. Overall HIV incidence was 0.085/100 PYAR, 95% confidence interval 0.02-0.25/100 PYAR.

conclusionThe data from Hai Phong clearly demonstrate that it is possible to achieve very low HIV incidence - 'end an HIV epidemic' - among PWID in a middle-income country.

Indexed as

Hepatitis CHIV InfectionsSubstance Abuse, IntravenousCohort StudiesCross-Sectional StudiesEpidemicsHumansIncidenceMalePrevalenceRisk-TakingVietnam

Identifiers

PMID33048884
PMCPMC8608372
OpenAlexW3092341811

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.