Evidence map›Paper›PMID 33048837›Full record

ArticleRadiology and oncology2020

Treatment patterns and real-world evidence for stage III non-small cell lung cancer in Central and Eastern Europe.

Milada Zemanova, Marko Jakopovic, Karmen Stanic, Małgorzata Łazar-Poniatowska, Martina Vrankar, Petronela Rusu, Tudor Ciuleanu, Davorin Radosavljevic, Krisztina Bogos, Sergiusz Nawrocki

Abstract read
In one paragraph

Article in Radiology and oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Milada Zemanova1st Faculty of Medicine of Charles University, Prague, Czech Republic.
Marko JakopovicDepartment for Respiratory Diseases Jordanovac, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, Zagreb, Croatia.
Karmen StanicInstitute of Oncology Ljubljana, Ljubljana, Slovenia.
Małgorzata Łazar-PoniatowskaDepartment of Oncology and Radiotherapy, Medical University of Gdansk, Gdansk, Poland.
Martina VrankarInstitute of Oncology Ljubljana, Ljubljana, Slovenia.
Petronela RusuInstitute of Oncology "Prof. Dr. Ion Chiricuta", Cluj-Napoca, Romania.
Tudor CiuleanuInstitute of Oncology "Prof. Dr. Ion Chiricuta", Cluj-Napoca, Romania.
Davorin RadosavljevicInstitute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Krisztina BogosNational Koranyi Institute of TB and Pulmonology, Budapest, Hungary.
Sergiusz NawrockiDepartment of Oncology, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The aim of this project was to collect real-world evidence and describe treatment patterns for stage III non-small cell lung cancer in Central and Eastern Europe. Based on real-world evidence, an expert opinion was developed, and the unmet needs and quality indicators were identified. Patients and methods A systematic literature search and a multidisciplinary expert panel of 10 physicians from 7 countries used a modified Delphi process to identify quality indicators and unmet needs in patients with stage III non-small cell lung cancer. The profound questionnaire was used to characterize treatment patterns used for stage III non-small cell lung cancer, and a systematic review identified patterns in Central and Eastern Europe. The first questionnaire was completed by a group of medical oncologists, radiation oncologists and pneumologists. The panel of experts attended an in-person meeting to review the results of the questionnaire and to process a second round Delphi. An additional survey was then compiled and completed by the panel. Results A complete consensus was reached by the panel of experts on a set of evidence-based clinical recommendations. The experience-based questionnaire generated a highly variable map of treatment patterns within the region. A list of unmet needs and barriers to quality care were developed with near-unanimous consent of the panel of experts. Conclusions The current landscape of diagnostic and therapeutic approaches in Central and Eastern European countries is highly variable. We identified several significant barriers, mainly related to the availability of diagnostic and imaging methods and low rates of chemoradiotherapy with curative intention as initial treatment for unresectable stage III NSCLC.

Indexed as

AdultCarcinoma, Non-Small-Cell LungConsensusDelphi TechniqueEuropeEurope, EasternEvidence-Based MedicineFemaleHumansLung NeoplasmsMaleNeoplasm StagingPractice Patterns, Physicians'Surveys and QuestionnairesDelphi methodexpert panelquality of carereal-world evidencestage III non-small cell lung cancertreatment patterns

Identifiers

PMID33048837
PMCPMC7585343

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.