Evidence map›Paper›PMID 33048340›Full record

SynthesisUpdates in surgery2021

Comparison of emergency cholecystectomy and delayed cholecystectomy after percutaneous transhepatic gallbladder drainage in patients with acute cholecystitis: a systematic review and meta-analysis.

Shao-Zhuo Huang, Hao-Qi Chen, Wei-Xin Liao, Wen-Ying Zhou, Jie-Huan Chen, Wen-Chao Li, Hui Zhou, Bo Liu, Kun-Peng Hu

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Updates in surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06048575 (Characteristics of the Attention Provided to Patients With Cholecystitis in Villavicencio Hospitals, Colombia), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06048575 completednot on this mapstarted 2025, after this paper: background citation

Characteristics of the Attention Provided to Patients With Cholecystitis in Villavicencio Hospitals, Colombia: A Retrospective Cross-sectional Trial.

TypeobservationalSponsorHospital Departamental de VillavicencioRan2025 to 2025Enrolled609ConditionsBiliary Tract DiseasesArmsCholecystectomy
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. C-reactive protein and digestive pathologies: A narrative review for daily clinical use.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Shao-Zhuo Huang *Department of General Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Hao-Qi Chen *Department of Hepatic Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Liver Transplantation, Guangzhou, China.
Wei-Xin Liao *Department of Infectious Diseases, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Wen-Ying ZhouDepartment of Laboratory Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jie-Huan ChenDepartment of Ultrasound, Binhaiwan Central Hospital of Dongguan, Dongguan, China.
Wen-Chao LiDepartment of General Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Hui ZhouDepartment of General Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Bo LiuDepartment of General Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. jakeliubo@qq.com.
Kun-Peng HuDepartment of General Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. hkpdhy918@126.com.
Sun Yat-sen University · CNThird Affiliated Hospital of Sun Yat-sen University · CNDongguan People’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laparoscopic cholecystectomy and percutaneous transhepatic gallbladder drainage (PTGBD) are common treatments for patients with acute cholecystitis. However, the safety and efficacy of emergency laparoscopic cholecystectomy (ELC) and delayed laparoscopic cholecystectomy (DLC) after PTGBD in patients with acute cholecystitis remain unclear. The PubMed, EMBASE, and Cochrane Library databases were searched through October 2019. The quality of the included nonrandomized studies was assessed using the Methodological Index for Nonrandomized Studies (MINORS). The meta-analysis was performed using STATA version 14.2. A random-effects model was used to calculate the outcomes. A total of fifteen studies involving 1780 patients with acute cholecystitis were included in the meta-analysis. DLC after PTGBD was associated with a shorter operative time (SMD - 0.51; 95% CI - 0.89 to - 0.13; P = 0.008), a lower conversion rate (RR 0.43; 95% CI 0.26 to 0.69; P = 0.001), less intraoperative blood loss (SMD - 0.59; 95% CI - 0.96 to - 0.22; P = 0.002) and longer time of total hospital stay compared to ELC (SMD 0.91; 95% CI 0.57-1.24; P < 0.001). There was no difference in the postoperative complications (RR 0.68; 95% CI 0.48-0.97; P = 0.035), biliary leakage (RR 0.65; 95% CI 0.34-1.22; P = 0.175) or mortality (RR 1.04; 95% CI 0.39-2.80; P = 0.933). Compared to ELC, DLC after PTGBD had the advantages of a shorter operative time, a lower conversion rate and less intraoperative blood loss.

Indexed as

Cholecystectomy, LaparoscopicCholecystitis, AcuteCholecystectomyDrainageHumansRetrospective StudiesTreatment OutcomeAcute cholecystitisCholecystectomyMeta-analysisPTGBD

Identifiers

PMID33048340
PMCPMC8005400
OpenAlexW3091935995

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.