Evidence map›Paper›PMID 33048338›Full record

ArticleActa neurologica Belgica2021

Recommendations for the treatment of epilepsy in adult and pediatric patients in Belgium: 2020 update.

Paul Boon, Susana Ferrao Santos, Anna C Jansen, Lieven Lagae, Benjamin Legros, Sarah Weckhuysen

Open access · hybridAbstract read
In one paragraph

Article in Acta neurologica Belgica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Paul BoonReference Center for Refractory Epilepsy, Department of Neurology, Ghent University Hospital, Ghent, Belgium. Paul.Boon@UZGent.be.ORCID http://orcid.org/0000-0002-4180-8896
Susana Ferrao Santos *Refractory Epilepsy Center, Saint-Luc University Hospital, Brussels, Belgium.ORCID http://orcid.org/0000-0001-6029-6235
Anna C Jansen *Pediatric Neurology Unit, Department of Pediatrics, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.ORCID http://orcid.org/0000-0002-3835-2824
Lieven Lagae *Reference Center for Refractory Epilepsy, Pediatric Neurology, Department of Development and Regeneration, University Hospitals Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-7118-0139
Benjamin Legros *Department of Neurology, Reference Center for the Treatment of Refractory Epilepsy, Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID http://orcid.org/0000-0002-9938-7457
Sarah Weckhuysen *Department of Neurology, Antwerp University Hospital, Antwerp, Belgium.ORCID http://orcid.org/0000-0003-2878-1147
Antwerp University Hospital · BECliniques Universitaires Saint-Luc · BEGhent University Hospital · BEKU Leuven · BEUniversité Libre de Bruxelles · BEVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To guide health care professionals in Belgium in selecting the appropriate antiepileptic drugs (AEDs) for their epilepsy patients, a group of Belgian epilepsy experts developed recommendations for AED treatment in adults and children (initial recommendations in 2008, updated in 2012). As new drugs have become available, others have been withdrawn, new indications have been approved and recommendations for pregnant women have changed, a new update was pertinent. A group of Belgian epilepsy experts (partly overlapping with the group in charge of the 2008/2012 recommendations) evaluated the most recent international guidelines and relevant literature for their applicability to the Belgian situation (registration status, reimbursement, clinical practice) and updated the recommendations for initial monotherapy in adults and children and add-on treatment in adults. Recommendations for add-on treatment in children were also included (not covered in the 2008/2012 publications). Like the 2008/2012 publications, the current update also covers other important aspects related to the management of epilepsy, including the importance of early referral in drug-resistant epilepsy, pharmacokinetic properties and tolerability of AEDs, comorbidities, specific considerations in elderly and pregnant patients, generic substitution and the rapidly evolving field of precision medicine.

Indexed as

AdolescentAdultAgedAnticonvulsantsBelgiumChildComorbidityDrug Therapy, CombinationEpilepsyFemaleHumansMaleMiddle AgedPractice Guidelines as TopicPregnancyTreatment OutcomeAnticonvulsantsAdd-on therapyAntiepileptic drugsEpilepsyMonotherapyRecommendationsSeizures

Identifiers

PMID33048338
PMCPMC7937601
OpenAlexW3092099292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.