SynthesisInternational journal of colorectal disease2021
A systemic review and metaanalysis of postoperative outcomes in urgent and elective bowel resection in patients with Crohn's disease.
Synthesis in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Increasing Rates of Bowel Resection Surgery for Stricturing Crohn's Disease in the Biologic Era.Inflammatory bowel diseases · 2025Article
- Comparison of outcomes in small bowel surgery for Crohn's disease: a retrospective NSQIP review.International journal of colorectal disease · 2024Article
- Factors influencing the outcomes of colonic resections for Crohn's colitis.International journal of colorectal disease · 2024Article
- Risk Factors for Complications and Disease Recurrence after Ileocecal Resection for Crohn's Disease in Children and Adults.Biomedicines · 2024Article
- The Enigma of Crohn's Disease: A Case Report.Cureus · 2024Article
- The Impact of Surgeon Speciality Interest on Outcomes of Emergency Laparotomy in IBD.World journal of surgery · 2023Article
- What is the real morbidity after emergency colectomy for Crohn's disease? A propensity score matched study.Techniques in coloproctology · 2023Article
- Early Anti-Tumor-Necrosis-Factor Therapy for Crohn's Disease-Related Abdominal Abscesses and Phlegmon in Children.Digestive diseases and sciences · 2023Article
- Perioperative optimization of Crohn's disease.Annals of gastroenterological surgery · 2023Review
- Clinical and surgical factors for successful stoma reversal in patients with Crohn's disease-results of a retrospective cohort study.International journal of colorectal disease · 2022Article
- It is not NOD2 - genetic and clinical risk factors for postoperative complications following ileocolic resection in Crohn's disease.International journal of colorectal disease · 2022Article
- Therapeutic strategies in Crohn's disease in an emergency surgical setting.World journal of gastroenterology · 2022Review
- Postoperative Use of Biologics was Less Common among Patients with Crohn's Disease With Emergent/Urgent Versus Elective Intestinal Resection.Gastro hep advances · 2022Article
- Article
- Real-World Outcomes of Patients Undergoing Open Colorectal Surgery with Wound Closure Incorporating Triclosan-Coated Barbed Sutures: A Multi-Institution, Retrospective Database Study.Medical devices (Auckland, N.Z.) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe study examined whether urgency of surgical intervention affects postoperative outcomes in patients with Crohn's disease (CD) undergoing bowel resection.
methodThe review was conducted according to a predefined, published study protocol in Prospero which is an international database of prospectively registered systematic reviews in health. The study reported according to PRIMSMA guidelines. We searched Embase and Pubmed for articles reporting postoperative outcome after urgent and elective surgery in patients with CD undergoing bowel resection. Primary outcome variable was 30-day overall postoperative complications while secondary outcome variables were intraabdominal septic complications (IASCs), mortality, reoperation, and readmission. Assessment of bias was performed using Newcastle-Ottawa score. Two authors independently extracted data on each study, patients, and outcome measures.
resultsThe search identified 22 studies in which 955 patients underwent urgent surgeries while 6518 patients underwent elective surgeries. Based on the quality assessment, 19 studies were classified as having high risk of bias, one study as having a medium risk of bias and 2 studies as having low risk of bias (≥ 8 stars). Random-effect metaanalysis showed urgent surgery was associated with ~ 40% increase in overall complications compared to elective surgery (RR = 1.43, 95% CI [1.09; 1.87], p = 0.010). IASCs also increased in patients who had urgent surgery (RR = 1.44, 95% CI [1.08; 1.92], p = 0.013). No significant difference was shown in mortality and readmission rates.
conclusionUrgent bowel resection in patients with CD is associated with higher risk of overall postoperative complications and IASCs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.