Evidence map›Paper›PMID 33048224›Full record

ArticleAbdominal radiology (New York)2020

The role of multiparametric resonance and biopsy in prostate cancer detection: comparison with definitive histological report after laparoscopic/robotic radical prostatectomy.

S Rapisarda, M Bada, F Crocetto, B Barone, D Arcaniolo, A Polara, C Imbimbo, G Grosso

Open access · hybridAbstract read
In one paragraph

Article in Abdominal radiology (New York), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

S RapisardaDepartment of Urology, Ospedale Pederzoli, Peschiera del Garda, Verona, Italy.
M BadaDepartment of Urology, San Bassiano Hospital, Bassano del Grappa, Vicenza, Italy.
F CrocettoDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, School of Medicine, Federico II University of Naples, Via Sergio Pansini, no 5, 80131, Naples, Italy. felice.crocetto@unina.it.ORCID http://orcid.org/0000-0002-4315-7660
B BaroneDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, School of Medicine, Federico II University of Naples, Via Sergio Pansini, no 5, 80131, Naples, Italy.
D ArcanioloDepartment of Woman, Child and General and Specialized Surgery, Urology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
A PolaraDepartment of Urology, Ospedale Pederzoli, Peschiera del Garda, Verona, Italy.
C ImbimboDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, School of Medicine, Federico II University of Naples, Via Sergio Pansini, no 5, 80131, Naples, Italy.
G GrossoDepartment of Urology, Ospedale Pederzoli, Peschiera del Garda, Verona, Italy.
University of Naples Federico II · ITFederico II University Hospital · ITOspedale San Bassiano · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMagnetic Resonance Imaging (MRI) targeted biopsy increases overall detection rates and decreases the risk of clinically insignificant PCa detection. The aim of this retrospective study is to compare concordance rates regarding side of lesion and Gleason Score at fusion targeted/systematic biopsy and MRI with the definitive histologic report of prostatectomy specimen.

methods115 patients underwent multiparametric (mp) MRI and successively fusion targeted/systematic biopsy. 107 patients, with a positive biopsy for PCa, further underwent laparoscopic/robotic radical prostatectomy. We compared surgical histologic report with biopsy histologic report for side of lesion and Gleason Score. We further compared PIRADS score at mpMRI with Gleason Score of both histologic reports.

resultsConcordance rate for mpMRI lesion side was 74% compared to biopsy and 52.3% compared to surgical histologic report (p < 0.0001). Fusion targeted/systematic biopsy reported a concordance rate with surgical histologic report of 67.3% for side of the lesion, while Gleason Score was concordant for 73.6% for clinically significant cancer (Gleason Score ≥ 7) (p < 0.0001). PIRADS score ≥ 3 was further associated with clinically significant cancer at surgical histologic report in 92.4% of cases (p = 0.359).

conclusionMultiparametric MRI of the prostate reaches a good and improvable accuracy in the detection of suspicious PCa before biopsy. A combined approach of fusion targeted and systematic biopsy could further increase the overall accuracy in PCa diagnosis, especially in biopsy-naïve patients, reaching concordance rates with definitive histologic report up to 52.3% and 85.5%.

Indexed as

LaparoscopyProstatic NeoplasmsRobotic Surgical ProceduresHumansImage-Guided BiopsyMagnetic Resonance ImagingMaleNeoplasm GradingProstatectomyRetrospective StudiesConcordance rateFusion biopsyMagnetic resonance imagingPIRADS

Identifiers

PMID33048224
PMCPMC7716945
OpenAlexW3092114839

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.