Evidence map›Paper›PMID 33048047›Full record

ArticleeLife2020

Extended field-of-view ultrathin microendoscopes for high-resolution two-photon imaging with minimal invasiveness.

Andrea Antonini, Andrea Sattin, Monica Moroni, Serena Bovetti, Claudio Moretti, Francesca Succol, Angelo Forli, Dania Vecchia, Vijayakumar P Rajamanickam, Andrea Bertoncini and 3 more

Abstract readEvaluation Study
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
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  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Fiber-basedNeurophotonics · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Characterizing close-focus lenses for microendoscopy.Journal of optical microsystems · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Andrea Antonini *Optical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.
Andrea Sattin *Optical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.
Monica MoroniNeural Coding Laboratory, Istituto Italiano di Tecnologia, Genova and Rovereto, Italy.ORCID 0000-0003-1852-7217
Serena BovettiOptical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.
Claudio MorettiOptical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.
Francesca SuccolOptical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.
Angelo ForliOptical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.
Dania VecchiaOptical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.ORCID 0000-0002-6091-538X
Vijayakumar P RajamanickamOptical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.
Andrea BertonciniBiological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Stefano PanzeriNeural Coding Laboratory, Istituto Italiano di Tecnologia, Genova and Rovereto, Italy.ORCID 0000-0003-1700-8909
Carlo LiberaleNanostructures Department, Istituto Italiano di Tecnologia, Genova, Italy.ORCID 0000-0002-5653-199X
Tommaso FellinOptical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.ORCID 0000-0003-2718-7533

Funding

Readout and control of spatiotemporal neuronal codes for behaviorU19NS107464 · NINDS · UNIVERSITY OF CHICAGO · PI SHOHAM, SHY · 2018 to 2022
$17.3M
Mapping of spatiotemporal code features to neural and perceptual spacesR01NS109961 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PANZERI, STEFANO VT, RINBERG, DMITRY · 2018 to 2022
$2.4M
The role of patterned activity in neuronal codes for behaviorU01NS090576 · NINDS · UNIVERSITY OF CHICAGO · PI FELLIN, TOMMASO, HISTED, MARK H · 2014 to 2016
$1.6M
FIRB RBAP11X42LKAUST BAS/1/1064-01-01King Abdullah University of Science and Technology BAS/1/1064-01-01NIH Brain Initiative NS090576NIH Brain Initiative NS107464NIH Brain Initiative NS109961NINDS NIH HHS R01 NS109961NINDS NIH HHS U01 NS090576NINDS NIH HHS U19 NS107464
6 · The paper itself

Abstract

Imaging neuronal activity with high and homogeneous spatial resolution across the field-of-view (FOV) and limited invasiveness in deep brain regions is fundamental for the progress of neuroscience, yet is a major technical challenge. We achieved this goal by correcting optical aberrations in gradient index lens-based ultrathin (≤500 µm) microendoscopes using aspheric microlenses generated through 3D-microprinting. Corrected microendoscopes had extended FOV (

Indexed as

AnimalsBehavior, AnimalEndoscopesFemaleMaleMiceMice, Inbred C57BLMicroscopy, Fluorescence, MultiphotonNeuronsThalamus3D microprintingAberration correctionmicroendoscopesmousenetwork dynamicsneurosciencethalamustwo-photon imaging

Identifiers

PMID33048047
PMCPMC7685710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.