Evidence map›Paper›PMID 33048032›Full record

ArticleRadiology2020

Multicenter Evaluation of Breast Cancer Screening with Digital Breast Tomosynthesis in Combination with Synthetic versus Digital Mammography.

Samantha P Zuckerman, Brian L Sprague, Donald L Weaver, Sally D Herschorn, Emily F Conant

Open access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Samantha P ZuckermanFrom the Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein Place, Philadelphia, PA 19104 (S.P.Z., E.F.C.); and Departments of Surgery (B.L.S.), Pathology (D.L.W.), and Radiology (S.D.H.), University of Vermont, University of Vermont Cancer Center, Burlington, Vt.ORCID 0000-0002-8872-2846
Brian L SpragueFrom the Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein Place, Philadelphia, PA 19104 (S.P.Z., E.F.C.); and Departments of Surgery (B.L.S.), Pathology (D.L.W.), and Radiology (S.D.H.), University of Vermont, University of Vermont Cancer Center, Burlington, Vt.ORCID 0000-0001-7948-8317
Donald L WeaverFrom the Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein Place, Philadelphia, PA 19104 (S.P.Z., E.F.C.); and Departments of Surgery (B.L.S.), Pathology (D.L.W.), and Radiology (S.D.H.), University of Vermont, University of Vermont Cancer Center, Burlington, Vt.
Sally D HerschornFrom the Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein Place, Philadelphia, PA 19104 (S.P.Z., E.F.C.); and Departments of Surgery (B.L.S.), Pathology (D.L.W.), and Radiology (S.D.H.), University of Vermont, University of Vermont Cancer Center, Burlington, Vt.ORCID 0000-0001-9331-644X
Emily F ConantFrom the Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein Place, Philadelphia, PA 19104 (S.P.Z., E.F.C.); and Departments of Surgery (B.L.S.), Pathology (D.L.W.), and Radiology (S.D.H.), University of Vermont, University of Vermont Cancer Center, Burlington, Vt.ORCID 0000-0002-8347-592X
Hospital of the University of Pennsylvania · US

Funding

Risk-based Imaging Strategies to Improve Breast Cancer Surveillance OutcomesP01CA154292 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KARLA M KERLIKOWSKE · 2011 to 2026
$52.9M
Penn Center for Innovation in Personalized Breast ScreeningU54CA163313 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ARMSTRONG, KATRINA, SCHNALL, MITCHELL D. · 2011 to 2017
$7.4M
Vermont Screening Process Documentation UnitU54CA163303 · NCI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SPRAGUE, BRIAN L · 2011 to 2017
$6.4M
Multi-center evaluation of digital breast tomosynthesis with synthesized two-dimensional mammography for breast cancer screeningR03CA223725 · NCI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI CONANT, EMILY, SPRAGUE, BRIAN L · 2018 to 2019
$172k
NCI NIH HHS P01 CA154292NCI NIH HHS R03 CA223725NCI NIH HHS U54 CA163303NCI NIH HHS U54 CA163313
6 · The paper itself

Abstract

BackgroundDigital breast tomosynthesis (DBT) combined with digital mammography (DM) is increasingly used in the United States instead of DM alone for breast cancer screening. Early screening outcomes incorporating synthetic mammography (SM) with DBT have suggested that SM is an acceptable non-radiation dose alternative to DM.PurposeTo compare multicenter outcomes from breast cancer screening with SM/DBT versus DM/DBT.Materials and MethodsThis was a retrospective study of consecutive screening mammograms obtained at two institutions. Eligible studies consisted of 34 106 DM/DBT examinations between October 3, 2011, and October 31, 2014, and 34 180 SM/DBT examinations between January 7, 2015, and February 2, 2018, at the University of Pennsylvania and 51 148 DM/DBT examinations between January 1, 2012, and May 31, 2016, and 31 929 SM/DBT examinations between June 1, 2016, and March 30, 2018, at the University of Vermont. Demographics of women who attended screening and results from screening were recorded. Recall rate, biopsy rate, false-negative rate, cancer detection rate, positive predictive value, sensitivity, and specificity were calculated according to modality and institution. Descriptive statistics, χ

Indexed as

AdultAgedAged, 80 and overArtifactsBiopsyBreast DensityBreast NeoplasmsEarly Detection of CancerFemaleHumansMammographyMass ScreeningMiddle AgedPredictive Value of TestsRadiographic Image Interpretation, Computer-AssistedRetrospective Studies

Identifiers

PMID33048032
PMCPMC7706877
OpenAlexW3092106995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.