ArticleActa paediatrica (Oslo, Norway : 1992)2021
A cross-sectional magnetic resonance imaging study of factors influencing growth plate closure in adolescents and young adults.
Article in Acta paediatrica (Oslo, Norway : 1992), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Magnetic resonance imaging of the knee for chronological age estimation-a systematic review.European radiology · 2023Pooled it
- Physeal Growth May Resume Following Removal of Transphyseal Epiphysiodesis Screws.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Article
- Kidney Volume and Molecular Processes are Dynamic in ADPKD.Kidney international reports · 2026Article
- Pediatric Climbers Experience More Upper Extremity Injuries, Geriatric Climbers More Lower Extremity Injuries, and Increased Shoulder Trauma Associated With Male Individuals in an Emergency Department Analysis of Rock Climbing-Associated Musculoskeletal Injuries.Arthroscopy, sports medicine, and rehabilitation · 2026Article
- Injuries according to sexual maturity status: a three-season observational study with male academy players of a professional Spanish football club.Biology of sport · 2026Article
- Discordance among skeletal maturity indicators: sources, interpretation, and clinical implications.Frontiers in pediatrics · 2026Review
- Effectiveness of synthetic vs. autologous ligaments in anterior cruciate ligament reconstruction with remnant preservation: a retrospective cohort study.Frontiers in sports and active living · 2026Article
- The effect of isotretinoin treatment for acne vulgaris on height in adolescents: A retrospective cohort study using the Rochester Epidemiology Project.Journal of the American Academy of Dermatology · 2025Article
- Discordance between knee and hand-wrist bone age in adolescents: implications for skeletal maturity assessment and its association with thyroid-stimulating hormone levels.Pediatric radiology · 2025Article
- X-linked hypophosphatemia and tumor-induced osteomalacia: a narrative review and expert opinion on the diagnostic and therapeutic challenges in the era of burosumab.Orphanet journal of rare diseases · 2025Review
- Lower limb injuries and their association with anthropometrics - an observational study of 381 German elite youth football players.BMC sports science, medicine & rehabilitation · 2025Article
- Exploring the impact of mechanical stimuli on growth plate morphology and trabecular adaptation: A finite element approach.Journal of orthopaedics · 2025Article
- Prevalence of orthodontic malocclusion in children aged 10-12: an epidemiological study.BMC oral health · 2025Article
- Margin of safety for needle puncture of a radial artery in children: Recommendation for ultrasound-guided cannulation.Journal of anesthesia · 2025Observational
- Commentary: MR-DTI of the growth plate: redefining concepts and evaluating future perspectives.Pediatric radiology · 2025Article
- Exploring Pediatric Vertebral, Sacral, and Pelvic Osteosarcomas through the NCDB: Demographics, Treatment Utilization, and Survival Outcomes.Children (Basel, Switzerland) · 2024Article
- Reliability of Two Recently Developed Procedures Assessing Biological Maturity by Ultrasound Imaging-A Pilot Study.Children (Basel, Switzerland) · 2024Article
- Specialist learning curves and clinical feasibility of introducing a new MRI grading system for skeletal maturity.BJR open · 2024Article
- Review
- Diffusion tensor imaging of the physis: the ABC's.Pediatric radiology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess growth plate fusion by magnetic resonance imaging (MRI) and evaluate the correlation with sex, age, pubertal development, physical activity and BMI.
methodsWrist, knee and ankle of 958 healthy subjects aged 14.0-21.5 years old were examined using MRI and graded by two radiologists. Correlations of growth plate fusion score with age, pubertal development, physical activity and BMI were assessed.
resultsComplete growth plate fusion occurred in 75%, 85%, 97%, 98%, 98% and 90%, 97%, 95%, 97%, 98% (radius, femur, proximal- and distal tibia and calcaneus) in 17-year-old females and 19-year-old males, respectively. Complete fusion occurs approximately 2 years earlier in girls than in boys. Pubertal development correlated with growth plate fusion score (ρ = 0.514-0.598 for the different growth plate sites) but regular physical activity did not. BMI also correlated with growth plate fusion (ρ = 0.186-0.384). Stratified logistic regression showed increased odds ratio (OR F: 2.65-8.71; M: 1.71-4.03) for growth plate fusion of obese or overweight subects versus normal-weight subjects. Inter-observer agreement was high (Κ = 0.87-0.94).
conclusionGrowth plate fusion can be assessed by MRI; occurs in an ascending order, from the foot to the wrist; and is significantly influenced by sex, pubertal development and BMI, but not by physical activity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.