Evidence map›Paper›PMID 33047258›Full record

Trial reportAIDS and behavior2021

A Randomized Trial Comparing Brief Advice and Motivational Interviewing for Persons with HIV-HCV Co-infection Who Drink Alcohol.

Michael D Stein, Debra S Herman, H Nina Kim, Abigail Howell, Audrey Lambert, Stephanie Madden, Ethan Moitra, Claire E Blevins, Bradley J Anderson, Lynn E Taylor and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02316184 (Comparing Brief Alcohol Interventions For HIV-HCV Co-infected Persons), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02316184 nacompletednot on this map

Comparing Brief Alcohol Interventions For HIV-HCV Co-infected Persons

TypeinterventionalSponsorButler HospitalRan2015 to 2022Enrolled300ConditionsHIV, Hepatitis CArmsMotivational Interviewing, Brief Advice
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Review
  8. Alcohol-related liver disease.Gastroenterology report · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Michael D SteinBehavioral Medicine and Addictions Research, Butler Hospital, Providence, RI, USA. mdstein@bu.edu.ORCID http://orcid.org/0000-0002-2466-5192
Debra S HermanBehavioral Medicine and Addictions Research, Butler Hospital, Providence, RI, USA.
H Nina KimDepartment of Medicine, University of Washington, Seattle, WA, USA.
Abigail HowellDepartment of Medicine, University of Washington, Seattle, WA, USA.
Audrey LambertDepartment of Health Law, Policy & Management, Boston University School of Public Health, 715 Albany Street, Boston, MA, 02118, USA.
Stephanie MaddenThe Miriam Hospital, Providence, RI, USA.
Ethan MoitraWarren Alpert Medical School of Brown University, Providence, RI, USA.
Claire E BlevinsBehavioral Medicine and Addictions Research, Butler Hospital, Providence, RI, USA.
Bradley J AndersonBehavioral Medicine and Addictions Research, Butler Hospital, Providence, RI, USA.
Lynn E TaylorUniversity of Rhode Island, Providence, RI, USA.
Megan M PinkstonWarren Alpert Medical School of Brown University, Providence, RI, USA.
Providence College · USBoston University · USUniversity of Washington · USBrown University · USUniversity of Rhode Island · US

Funding

Comparing Brief Alcohol Interventions for HIV-HCV Co-infected PersonsR01AA023726 · NIAAA · BUTLER HOSPITAL (PROVIDENCE, RI) · PI PINKSTON, MEGAN M, STEIN, MICHAEL D · 2014 to 2018
$2.5M
NIAAA NIH HHS R01 AA023726NIAAA NIH HHS RO1 AA023726
6 · The paper itself

Abstract

Alcohol use contributes to the progression of liver disease in HIV-HCV co-infected persons, but alcohol interventions have never addressed low levels of alcohol use in this population. We enrolled 110 persons consuming at least 4 alcoholic drinks weekly in a clinical trial comparing two active 18-month long interventions, delivered every 3 months by phone, brief advice about drinking versus a motivational intervention. Final assessment was at 24 months. MI had larger reductions in alcohol use days than the BA arm at all follow-up assessments. The treatment by time effect was not significant for days of drinking (p = 0.470), mean drinks per day (p = 0.155), or for the continuous FIB-4 index (p = 0.175). Drinking declined in both conditions from baseline, but given the small sample, we do not have sufficient data to make any conclusion that one treatment is superior to the other.Trial Registry Trial registered at clinicaltrials.gov; Clinical Trial NCT02316184.

Indexed as

CoinfectionHepatitis CHIV InfectionsMotivational InterviewingAlcohol DrinkingCrisis InterventionHumansAlcohol useBrief adviceFIB-4HIV–HCV co-infectionMotivational intervention

Identifiers

PMID33047258
OpenAlexW3091997065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.