Evidence map›Paper›PMID 33046889›Full record

ArticleNature immunology2020

Transcriptome dynamics of CD4

Megan S F Soon, Hyun Jae Lee, Jessica A Engel, Jasmin Straube, Bryce S Thomas, Clara P S Pernold, Lachlan S Clarke, Pawat Laohamonthonkul, Rohit N Haldar, Cameron G Williams and 16 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. T follicular helper cell development during malaria.Current opinion in immunology · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. CD4Nature communications · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 7 institutions in 6 countries.

Megan S F Soon *QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Hyun Jae Lee *QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Jessica A Engel *QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Jasmin StraubeQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-1748-0659
Bryce S ThomasQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Clara P S PernoldQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Lachlan S ClarkeQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0003-0342-9040
Pawat LaohamonthonkulQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Rohit N HaldarQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Cameron G WilliamsQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Lianne I M LansinkQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Marcela L MoreiraDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0003-3477-0727
Michael BramhallDepartment of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.
Lambros T KoufariotisQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Scott WoodQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0003-4543-8850
Xi ChenDepartment of Biology, South University of Science and Technology of China, Shenzhen, China.ORCID http://orcid.org/0000-0003-2648-3146
Kylie R JamesWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID http://orcid.org/0000-0002-7107-0650
Tapio LönnbergTurku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
Steven W LaneQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Gabrielle T BelzThe University of Queensland Diamantina Institute, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-9660-9587
Christian R EngwerdaQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
David S KhouryKirby Institute, University of New South Wales, Kensington, Sydney, New South Wales, Australia.
Miles P DavenportKirby Institute, University of New South Wales, Kensington, Sydney, New South Wales, Australia.
Valentine SvenssonDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Sarah A TeichmannWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. st9@sanger.ac.uk.ORCID http://orcid.org/0000-0002-6294-6366
Ashraful HaqueQIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia. ashraful.haque@unimelb.edu.au.ORCID http://orcid.org/0000-0003-2260-0026
QIMR Berghofer Medical Research Institute · AUThe University of Melbourne · AUUniversity of Cambridge · GBUNSW Sydney · AUÅbo Akademi University · FICalifornia Institute of Technology · USThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamics of CD4

Indexed as

Immunologic MemoryTranscriptomeAdoptive TransferAnimalsAntimalarialsBiomarkersCD4-Positive T-LymphocytesChromatinDisease Models, AnimalGene Expression ProfilingHumansMalariaMicePlasmodiumAntimalarialsBiomarkersChromatin

Identifiers

PMID33046889
OpenAlexW3091910761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.