Evidence map›Paper›PMID 33046688›Full record

Trial reportBlood cancer journal2020

ASXL1 mutation confers poor prognosis in primary myelofibrosis patients with low JAK2V617F allele burden but not in those with high allele burden.

Yu-Hung Wang, Chien-Chin Lin, Sze-Hwei Lee, Xavier Cheng-Hong Tsai, Shan-Ju Wu, Hsin-An Hou, Tai-Chung Huang, Yuan-Yeh Kuo, Ming Yao, Koping Chang and 6 more

Abstract readClinical TrialLetter
In one paragraph

Trial report in Blood cancer journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Molecular profiling in MPN: who should have it and why?Hematology. American Society of Hematology. Education Program · 2024
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Molecular Pathogenesis of Myeloproliferative Neoplasms.Current hematologic malignancy reports · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yu-Hung Wang *Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.ORCID 0000-0003-4483-5627
Chien-Chin Lin *Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Sze-Hwei LeeGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Xavier Cheng-Hong TsaiDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID 0000-0002-4174-8766
Shan-Ju WuDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Hsin-An HouDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Tai-Chung HuangDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID 0000-0002-1625-7295
Yuan-Yeh KuoTai-Cheng Stem Cell Therapy Center, National Taiwan University, Taipei, Taiwan.ORCID 0000-0002-6090-9000
Ming YaoDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Koping ChangDepartment of Pathology, National Taiwan University Hospital, Taipei, Taiwan.
Chung-Wu LinDepartment of Pathology, National Taiwan University Hospital, Taipei, Taiwan.
Yun-Chu LinDepartment of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.
Fen-Ming TienDepartment of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.ORCID 0000-0003-4513-2472
Wen-Chien ChouDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID 0000-0003-2967-698X
Jih-Luh TangDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. tangntuh@gmail.com.ORCID 0000-0003-4021-3281
Hwei-Fang TienDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID 0000-0002-1384-5593

Funding

Ministry of Health and Welfare (Ministry of Health and Welfare, Taiwan) MOHW 107-TDU-B-211-114009Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) MOST 107-2314-B-002-013
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mutation, MissensePrimary MyelofibrosisAgedAllelesAmino Acid SubstitutionDisease-Free SurvivalFemaleHumansJanus Kinase 2MaleMiddle AgedRepressor ProteinsRetrospective StudiesSurvival RateASXL1 protein, humanJAK2 protein, humanJanus Kinase 2Repressor Proteins

Identifiers

PMID33046688
PMCPMC7550588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.