Evidence map›Paper›PMID 33046684›Full record

ArticleJournal of microbiology and biotechnology2020

The Effect of Milk Protein on the Biological and Rheological Properties of Probiotic Capsules.

Bum Ju Kil, Sung Jin Yoon, Cheol-Heui Yun, Chul-Sung Huh

Open access · bronzeAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. ProbioticNarra J · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bum Ju KilBiomodulation major and Center for Food and Bioconvergence, Seoul National University, Seoul 08826, Republic of Korea.
Sung Jin YoonDepartment of Food Science and Biotechnology, Dongguk University-Seoul, Goyang 10326, Republic of Korea.
Cheol-Heui YunBiomodulation major and Center for Food and Bioconvergence, Seoul National University, Seoul 08826, Republic of Korea.
Chul-Sung HuhInstitute of Green-Bio Science and Technology, Seoul National University, Pyeongchang-gun 25354, Republic of Korea.
Seoul National University · KRDongguk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics are often infused into functional foods or encapsulated in a supplement form to maintain a healthy balance between the gut microbiota and their host. Because there are milk-based functional foods such as yogurt and cheese on the market, it has been suggested that milk-based probiotics could be incorporated into skim milk proteins in a liquid capsule. Skim milk is mainly composed of casein and whey protein, which create a strong natural barrier and can be used to encapsulate probiotics. In this study, we compared the encapsulated probiotics prepared with milkbased concentrated cell mixtures using commercial probiotics. Probiotic capsules were emulsified with skim milk proteins using vegetable oil to form a double coating layer. The product was heatstable when tested using a rheometer. The survival rate of the milk-based probiotic cells in the lower gastric environment with bile was significantly higher than commercial probiotics. Thus, milkencapsulated probiotics exhibited greater efficacy in the host than other types of probiotics, suggesting that the former could be more viable with a longer shelf life under harsh conditions than other form of probiotics. Our findings suggested that, compared with other types of probiotics, milkbased probiotics may be a better choice for producers and consumers.

Indexed as

RheologyAnimalsBileCapsulesCaseinsCheeseFunctional FoodMilkMilk ProteinsProbioticsTemperatureThermotoleranceYogurtCapsulesCaseinsMilk Proteinsmilk-probiotic capsulesProbioticstemperature-sensitive

Identifiers

PMID33046684
PMCPMC9728249
OpenAlexW3091855967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.