ArticleThorax2020
Parental psychological distress during pregnancy and the risk of childhood lower lung function and asthma: a population-based prospective cohort study.
Article in Thorax, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.
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Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Perinatal maternal depression and the risk of childhood asthma in offspring: A meta-analysis.PloS one · 2024Pooled it
- Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation.Molecular psychiatry · 2023Pooled it
- Joint modelling of wheeze and lung function from childhood to early adulthood: four population-based birth cohorts.EClinicalMedicine · 2026Article
- Maternal eating disorders and respiratory outcomes in childhood: findings from the EU Child Cohort Network.Thorax · 2026Article
- Defining and Promoting Pediatric Pulmonary Health: Assessing Lung Function and Structure.Pediatrics · 2023Article
- Investigating the role of relationship satisfaction and paternal psychological distress during pregnancy on offspring health in early life.BJPsych open · 2023Article
- European Respiratory Society International Congress 2021: highlights from best-abstract awardees.Breathe (Sheffield, England) · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough maternal psychological distress during pregnancy is associated with increased risks of respiratory morbidity in preschool children, it is unknown whether this association persists into later childhood.
objectiveTo examine the association between parental psychological distress during pregnancy and lung function and asthma in children of school age.
methodsThis study of 4231 children was embedded in a population-based prospective cohort. Parental psychological distress was assessed by the Brief Symptom Inventory during and 3 years after pregnancy, and in mothers also at 2 and 6 months after pregnancy. At age 10 years, lung function was obtained by spirometry and asthma by questionnaire.
resultsThe prevalence of asthma was 5.9%. Maternal overall psychological distress during pregnancy was associated with a lower forced vital capacity (FVC) (z-score difference -0.10 (95% CI -0.20 to -0.01) per 1-unit increase), maternal depressive symptoms during pregnancy with a lower forced expiratory volume in the first second (FEV
conclusionMaternal, but not paternal, psychological distress during pregnancy is associated with an increased risk of asthma and partly lower lung function in children. This suggests intrauterine programming for the risk of later-life respiratory disease.
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