Evidence map›Paper›PMID 33046527›Full record

Trial reportHeart (British Cardiac Society)2020

Changes in quality of life, cognition and functional status following catheter ablation of atrial fibrillation.

Jonathan P Piccini, Derick M Todd, Tyler Massaro, Aimee Lougee, Karl Georg Haeusler, Benjamin Blank, Joseph Paul de Bono, David J Callans, Arif Elvan, Thomas Fetsch and 16 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Heart (British Cardiac Society), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Impact of catheter ablation versus medical therapy on cognitive function in atrial fibrillation: a systematic review.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022
    Pooled it
  2. Article
  3. Review
  4. Observational
  5. Review
  6. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 19 institutions in 11 countries.

Jonathan P PicciniDivision of Cardiology, Duke University Medical Center & Duke Clinical Research Institute, Durham, North Carolina, USA jonathan.piccini@duke.edu.ORCID 0000-0003-0772-2404
Derick M ToddCardiology, Liverpool Heart and Chest Hospital, Liverpool, UK.
Tyler MassaroBiostatistics, Duke University Medical Center, Durham, North Carolina, USA.
Aimee LougeeBiostatistics, Duke Clinical Research Institute, Durham, North Carolina, USA.
Karl Georg HaeuslerDepartment of Neurology, Universitätsklinikum Würzburg, Wurzburg, Germany.
Benjamin BlankAtrial Fibrillation NETwork association (AFNET), Munster, Germany.
Joseph Paul de BonoInstitute of Cardiovascular Sciences, University Hospital Birmingham, Birmingham, West Midlands, UK.
David J CallansMedicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Arif ElvanCardiology, Isala Klinieken, Zwolle, The Netherlands.
Thomas FetschCardiology, The Clinical Research Institute, Muncher, Germany.
Isabelle Van GelderCardiology, University Medical Centre Groningen Thorax Centre, Groningen, The Netherlands.
Philip GentleskCardiology, Sentara Norfolk General Hospital, Norfolk, Virginia, USA.
Massimo GrimaldiEnte Ecclesiastico Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, Puglia, Italy.
Jim HansenDepartment of Cardiology, Gentofte Hospital, Gentofte, Hovedstaden, Denmark.
Gerhard HindricksCardiology, University of Leipzig, Leipzig, Germany.
Hussein Al-KhalidiDuke Clinical Research Institute, Durham, North Carolina, USA.
Lluis MontCardiovascular Institute, University of Barcelona, Barcelona, Spain.
Jens Cosedis NielsenCardiology B, Aarhus University Hospital, Aarhus N, Denmark.
Georg NoelkerDepartment of Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Tom De PotterCardiology, Onze Lieve Vrouw Ziekenhuis, Aalst, Belgium.
Daniel ScherrCardiology, Medical University of Graz, Graz, Austria.
Ulrich SchottenPhysiology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Sakis ThemistoclakisCardiology, Ospedale Dell'Angelo, Mestre-Venice, Italy.
Johan VijgenHeart Center, Jessa Hospital, Hasselt, Belgium.
Luigi Di BiaseCardiology, Montefiore Medical Center, Bronx, New York, USA.
Paulus KirchhofAtrial Fibrillation NETwork association (AFNET), Munster, Germany.ORCID 0000-0002-1881-0197
Clinical Research Institute · USCardiovascular Institute Hospital · JPInstitute of Cardiology · PLAarhus University Hospital · DKAtrial Fibrillation NETwork · DEDuke University · USEuropean Neuroendocrine Tumor Society · DEGentofte Hospital · DKHeart and Diabetes Center North Rhine-Westphalia · DEJessa Hospital · BEMaastricht University Medical Centre · NLMedical University of Graz · ATMontefiore Medical Center · USOnze Lieve Vrouwziekenhuis Hospital · BEOspedale Generale Regionale Francesco Miulli · ITSentara Norfolk General Hospital · USUniversity Medical Center Groningen · NLUniversity of Liverpool · GBUniversity of Pennsylvania · US

Funding

British Heart Foundation AA/18/2/34218British Heart Foundation FS/13/43/30324
6 · The paper itself

Abstract

objectiveTo investigate changes in quality of life (QoL), cognition and functional status according to arrhythmia recurrence after atrial fibrillation (AF) ablation.

methodsWe compared QoL, cognition and functional status in patients with recurrent atrial tachycardia (AT)/AF versus those without recurrent AT/AF in the AXAFA-AFNET 5 clinical trial. We also sought to identify factors associated with improvement in QoL and functional status following AF ablation by overall change scores with and without analysis of covariance (ANCOVA).

resultsAmong 518 patients who underwent AF ablation, 154 (29.7%) experienced recurrent AT/AF at 3 months. Patients with recurrent AT/AF had higher mean CHA

conclusionsPatients without recurrent AT/AF appear to experience greater improvement in functional status but similar QoL as those with recurrent AT/AF after AF ablation.

Indexed as

Functional StatusQuality of LifeAgedAtrial FibrillationCatheter AblationCognitionFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesRecurrenceRisk FactorsSingle-Blind MethodTreatment Outcomeatrial arrhythmia ablation proceduresatrial fibrillationquality and outcomes of care

Identifiers

PMID33046527
PMCPMC7719908
OpenAlexW3092597781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.