Feeding management before gastrointestinal studies in pigs.

Rachael Gregson, Stephen Greenhalgh, Benjamin Cox, Sandy Cochrane, R Eddie Clutton

Open access · hybridAbstract read

In one paragraph

Article in Laboratory animals, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 40% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rachael GregsonWellcome Critical Care Laboratory for Large Animals, Dryden Farm, University of Edinburgh, UK.ORCID https://orcid.org/0000-0003-2704-1825

Stephen GreenhalghWellcome Critical Care Laboratory for Large Animals, Dryden Farm, University of Edinburgh, UK.

Benjamin CoxDivision of Imaging and Technology, School of Medicine, University of Dundee, UK.

Sandy CochraneJames Watt South Building, James Watt School of Engineering, University of Glasgow, UK.

R Eddie CluttonWellcome Critical Care Laboratory for Large Animals, Dryden Farm, University of Edinburgh, UK.

University of Edinburgh · GBHeriot-Watt University · GBUniversity of Dundee · GB

Funding

Wellcome Trust

6 · The paper itself

Abstract

Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.

Indexed as

DietAnimal HusbandryAnimalsCapsule EndoscopesCapsule EndoscopyFemaleIntestine, SmallModels, AnimalSus scrofaanaesthesiacapsule endoscopycolorectal surgeryfood withdrawalgastrointestinal tractPigsrefinement

Identifiers

PMID33045909

DOI10.1177/0023677220960509

PMCPMC8044613

OpenAlexW3092106987

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.