Evidence map›Paper›PMID 33045888›Full record

ArticleThe Journal of international medical research2020

Clinical manifestations and laboratory results of 61 children with infectious mononucleosis.

Yanming Wu, Suli Ma, Lingjun Zhang, Daoming Zu, Fangjin Gu, Xiaoyuan Ding, Lei Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

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  18. HLA-DR Expression Level in CD8Frontiers in immunology · 2021
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yanming WuDepartment of Pediatrics, People's Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Suli MaDepartment of Pediatrics, People's Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Lingjun ZhangDepartment of Pediatrics, People's Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Daoming ZuDepartment of Pediatrics, People's Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Fangjin GuDepartment of Pediatrics, People's Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Xiaoyuan DingDepartment of Pediatrics, People's Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Lei ZhangDepartment of Pediatrics, People's Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China.ORCID https://orcid.org/0000-0003-3564-495X
Shanghai University of Medicine and Health Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the clinical manifestations of infectious mononucleosis in children of different ages.

methodsClinical data from pediatric patients with infectious mononucleosis admitted from May 2015 to April 2019 were retrospectively analyzed. Patients were stratified into three groups (age 1-3 years, 4-6 years, and 7-14 years) for analysis of clinical and laboratory results.

resultsData from 61 patients (male:female ratio 1.18:1) aged 5.15 ± 2.93 years (mean ± standard deviation; range: 1-14 years) were analyzed. Infectious mononucleosis occurred throughout the year and the main clinical manifestations were fever (98.3%), tonsillitis (100%), tonsillar white exudate (83.6%), cervical lymphadenopathy (98.3%), hepatomegaly (37.7%), splenomegaly (42.6%), eyelid edema (41.0%), and nasal obstruction (49.2%). Disease onset was most common during early childhood (37.7%) and at preschool age (37.7%). Younger children had more obvious symptoms of nasal obstruction and older children had more significant elevations of alanine aminotransferase and higher percentages of atypical lymphocytes.

conclusionThe clinical manifestations of infectious mononucleosis in children differed by age. These associations required attention for clinical decision making.

Indexed as

Infectious MononucleosisAdolescentAlanine TransaminaseChildChild, PreschoolFemaleHerpesvirus 4, HumanHumansInfantMaleRetrospective StudiesAlanine Transaminaseage stagingclinical manifestationsEpstein–Barr virusinfectious mononucleosislaboratory resultsretrospective analysis

Identifiers

PMID33045888
PMCPMC7563853
OpenAlexW3091778503

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.