Evidence map›Paper›PMID 33045772›Full record

ArticleJournal of Korean medical science2020

The Implication of Cardiac Injury Score on In-hospital Mortality of Coronavirus Disease 2019.

In Cheol Kim, Jin Eun Song, Hee Jung Lee, Jeong Ho Park, Miri Hyun, Ji Yeon Lee, Hyun Ah Kim, Yong Shik Kwon, Jae Seok Park, Jong Chan Youn and 10 more

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. ABCInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

In Cheol KimDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-5751-2328
Jin Eun SongDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-5939-9912
Hee Jung LeeDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-0243-6954
Jeong Ho ParkDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-5892-7226
Miri HyunDivision of Infectious Disease, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0003-0062-342X
Ji Yeon LeeDivision of Infectious Disease, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-2788-1392
Hyun Ah KimDivision of Infectious Disease, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-9125-7156
Yong Shik KwonDivision of Pulmonology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-8003-7668
Jae Seok ParkDivision of Pulmonology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-5751-7209
Jong Chan YounDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-0998-503X
Jongmin HwangDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0001-9710-0945
Cheol Hyun LeeDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0003-4203-1457
Yun Kyeong ChoDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-0221-0971
Hyoung Seob ParkDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-8042-1029
Hyuck Jun YoonDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-0563-7014
Chang Wook NamDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-3370-5774
Seongwook HanDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-0496-7249
Seung Ho HurDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-3895-1915
Howard J EisenHeart and Vascular Institute, Pennsylvania State University, Milton S. Hershey Medical Center, Hershey, PA, USA.ORCID https://orcid.org/0000-0003-1149-4344
Hyungseop KimDivision of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Korea. khyungseop@dsmc.or.kr.ORCID https://orcid.org/0000-0001-7056-4221

Funding

Korea Health Industry Development Institute H18C1234
6 · The paper itself

Abstract

backgroundsThe severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has spread worldwide. Cardiac injury after SARS-CoV-2 infection is a major concern. The present study investigated impact of the biomarkers indicating cardiac injury in coronavirus disease 2019 (COVID-19) on patients' outcomes.

methodsThis study enrolled patients who were confirmed to have COVID-19 and admitted at a tertiary university referral hospital between February 19, 2020 and March 15, 2020. Cardiac injury was defined as an abnormality in one of the following result markers: 1) myocardial damage marker (creatine kinase-MB or troponin-I), 2) heart failure marker (N-terminal-pro B-type natriuretic peptide), and 3) electrical abnormality marker (electrocardiography). The relationship between each cardiac injury marker and mortality was evaluated. Survival analysis of mortality according to the scoring by numbers of cardiac injury markers was also performed.

resultsA total of 38 patients with COVID-19 were enrolled. Twenty-two patients (57.9%) had at least one of cardiac injury markers. The patients with cardiac injuries were older (69.6 ± 14.9 vs. 58.6 ± 13.9 years old,

conclusionThe increased number of cardiac injury markers is related to in-hospital mortality in patients with COVID-19.

Indexed as

AgedAged, 80 and overAge FactorsBetacoronavirusCoronavirus InfectionsCOVID-19Creatine Kinase, MB FormElectrocardiographyFemaleHeart InjuriesHospital MortalityHumansKaplan-Meier EstimateMaleMiddle AgedMyocardiumCreatine Kinase, MB FormNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Troponin ICoronavirusCOVID-19, Cardiac Injury MarkersIn-hospital Mortality

Identifiers

PMID33045772
PMCPMC7550234

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.