Evidence map›Paper›PMID 33045736›Full record

ArticleNeurosurgery2021

Three-Tesla Magnetic Resonance Imaging of Patients With Deep Brain Stimulators: Results From a Phantom Study and a Pilot Study in Patients.

Benjamin Davidson, Fred Tam, Benson Yang, Ying Meng, Clement Hamani, Simon J Graham, Nir Lipsman

Open access · greenAbstract read
In one paragraph

Article in Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Optimizing the trajectory of deep brain stimulation leads reduces RF heating during MRI at 3 T: Characteristics and clinical translation.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Benjamin DavidsonDivision of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Fred TamPhysical Sciences Platform, Sunnybrook Research Institute, Toronto, Canada.
Benson YangPhysical Sciences Platform, Sunnybrook Research Institute, Toronto, Canada.
Ying MengDivision of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Clement HamaniDivision of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Simon J GrahamSunnybrook Research Institute, Toronto, Canada.
Nir LipsmanDivision of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Sunnybrook Health Science Centre · CASunnybrook Hospital · CAUniversity of Toronto · CA

Funding

CIHR
6 · The paper itself

Abstract

backgroundDeep brain stimulation (DBS) is a standard of care treatment for multiple neurologic disorders. Although 3-tesla (3T) magnetic resonance imaging (MRI) has become the gold-standard modality for structural and functional imaging, most centers refrain from 3T imaging in patients with DBS devices in place because of safety concerns. 3T MRI could be used not only for structural imaging, but also for functional MRI to study the effects of DBS on neurocircuitry and optimize programming.

objectiveTo use an anthropomorphic phantom design to perform temperature and voltage safety testing on an activated DBS device during 3T imaging.

methodsAn anthropomorphic 3D-printed human phantom was constructed and used to perform temperature and voltage testing on a DBS device during 3T MRI. Based on the phantom assessment, a cohort study was conducted in which 6 human patients underwent MRI with their DBS device in an activated (ON) state.

resultsDuring the phantom study, temperature rises were under 2°C during all sequences, with the DBS in both the deactivated and activated states. Radiofrequency pulses from the MRI appeared to modulate the electrical discharge from the DBS, resulting in slight fluctuations of voltage amplitude. Six human subjects underwent MRI with their DBS in an activated state without any serious adverse events. One patient experienced stimulation-related side effects during T1-MPRAGE scanning with the DBS in an ON state because of radiofrequency-induced modulation of voltage amplitude.

conclusionFollowing careful phantom-based safety testing, 3T structural and functional MRI can be safely performed in subjects with activated deep brain stimulators.

Indexed as

Deep Brain StimulationPhantoms, ImagingAgedBrainCohort StudiesElectrodes, ImplantedFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsPrinting, Three-DimensionalTemperatureDeep brain stimulationMagnetic resonance imagingPhantomPsychiatric surgeryRadiofrequency heating

Identifiers

PMID33045736
PMCPMC7803432
OpenAlexW3092474402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.