Evidence map›Paper›PMID 33045642›Full record

ArticleAddictive behaviors2021

Intersection of familial risk and environmental social control on high-risk drinking and alcohol dependence in a US national sample of adults.

Katherine J Karriker-Jaffe, Karen G Chartier, Cristina B Bares, Kenneth S Kendler, Thomas K Greenfield

Open access · greenAbstract read
In one paragraph

Article in Addictive behaviors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
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  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Katherine J Karriker-JaffeAlcohol Research Group, Public Health Institute, Emeryville, CA 94608-1010, USA. Electronic address: kkarrikerjaffe@rti.org.
Karen G ChartierVirginia Commonwealth University, School of Social Work and Department of Psychiatry, Richmond, VA 23284, USA.
Cristina B BaresUniversity of Michigan, School of Social Work, Ann Arbor, MI 48109, USA.
Kenneth S KendlerVirginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry and Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23284, USA.
Thomas K GreenfieldAlcohol Research Group, Public Health Institute, Emeryville, CA 94608-1010, USA.
Virginia Commonwealth University · USAlcohol Research Group · USPublic Health Institute · USUniversity of Michigan–Ann Arbor · US

Funding

TREND &STRUCTURE OF ALCOHOL DEPENDENCE--GENERAL POPULATION 1990 SURVEY DATAP50AA005595 · NIAAA · WESTERN CONSORTIUM FOR PUBLIC HEALTH · PI MARTINEZ, PRISCILLA · 1985 to 2025
$34.1M
Genetic Contributions to Smoking and Internalizing Problems in AdolescenceK01DA036681 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI BARES, CRISTINA B. · 2014 to 2018
$755k
Ethnicity and alcohol dependence: Phenotypes, genes, and the social environmentK01AA021145 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI CHARTIER, KAREN G. · 2012 to 2016
$536k
NIAAA NIH HHS K01 AA021145NIAAA NIH HHS P50 AA005595NIDA NIH HHS K01 DA036681
6 · The paper itself

Abstract

backgroundEffects of a family history of alcoholism may be moderated by area-level social control factors. We examine whether increased neighborhood alcohol availability (low social control environment) or increased presence of religious adherents in the county (high social control environment) interact with family history in relation to alcohol outcomes.

methodsWeighted data from 12,686 adult drinkers (51% male; mean age 44; 80% White, 9% Black, 11% Hispanic) in three US National Alcohol Surveys were linked with data on area-level off-premise alcohol availability and adherence to religions with strong prohibitions against drinking. Family history density had four levels (family history negative, extended family only, first-degree relative(s) only, high family density). Dichotomous outcomes were past-year high-risk drinking and alcohol dependence. Logistic regression models with interaction terms assessed whether associations of family history with alcohol outcomes differed significantly by area-level social control. Stratified models assessed differences by sex and by race/ethnicity.

resultsIn the full sample, effects of first-degree relatives and high family density on high-risk drinking strengthened as alcohol availability increased. This was replicated in the subsample of women and suggested in relation to dependence among men and Black drinkers. For White drinkers, higher religious social control reduced effects of first-degree relatives on high-risk drinking.

conclusionsLow social control-in particular, greater density of off-premise alcohol outlets-appears to exacerbate effects of a family history of alcoholism on high-risk drinking. Policy makers should consider differential benefits of decreasing alcohol availability for people from high-risk families to reduce high-risk drinking and alcohol problems.

Indexed as

AlcoholismAdultAlcohol DrinkingFemaleGenetic Predisposition to DiseaseHumansMaleRisk FactorsSocial Control, FormalAlcohol use disorderFamily historyGender differencesNeighborhood environmentRacial/ethnic differencesSocial control

Identifiers

PMID33045642
PMCPMC7524522
OpenAlexW3091754140

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.