Evidence map›Paper›PMID 33044646›Full record

ArticleAnnals of intensive care2020

Use of critical care resources during the first 2 weeks (February 24-March 8, 2020) of the Covid-19 outbreak in Italy.

Tommaso Tonetti, Giacomo Grasselli, Alberto Zanella, Giacinto Pizzilli, Roberto Fumagalli, Simone Piva, Luca Lorini, Giorgio Iotti, Giuseppe Foti, Sergio Colombo and 23 more

Abstract read
In one paragraph

Article in Annals of intensive care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Tommaso TonettiAlma Mater Studiorum, Dipartimento Di Scienze Mediche E Chirurgiche, Anesthesia and Intensive Care Medicine, Università Di Bologna, Policlinico Di Sant'Orsola, Via Massarenti, 9 40138, Bologna, Italy. tommaso.tonetti@unibo.it.ORCID http://orcid.org/0000-0001-9676-3595
Giacomo GrasselliFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Alberto ZanellaFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Giacinto PizzilliAlma Mater Studiorum, Dipartimento Di Scienze Mediche E Chirurgiche, Anesthesia and Intensive Care Medicine, Università Di Bologna, Policlinico Di Sant'Orsola, Via Massarenti, 9 40138, Bologna, Italy.
Roberto FumagalliAnesthesia and Critical Care, ASST Grande Ospedale Metropolitano Niguarda, University of Milano-Bicocca, Milan, Italy.
Simone PivaAnesthesia and Critical Care, ASST Spedali Civili, University of Brescia, Brescia, Italy.
Luca LoriniAnesthesia and Critical Care, ASST Papa Giovanni XXIII, Bergamo, Italy.
Giorgio IottiAnesthesia and Critical Care, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Giuseppe FotiAnesthesia and Critical Care, ASST Ospedale San Gerardo Di Monza, University of Milano-Bicocca, Milan, Italy.
Sergio ColomboAnesthesia and Critical Care, IRCCS San Raffaele Scientific Institute, Università Vita-Salute San Raffaele, Milan, Italy.
Luigi VivonaFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Sandra RossiAnesthesia and Critical Care, Azienda Ospedaliero-Universitaria Di Parma, Parma, Italy.
Massimo GirardisAnesthesia and Critical Care, Policlinico Di Modena, Università Di Modena E Reggio Emilia, Modena, Italy.
Vanni AgnolettiAnesthesia and Critical Care Ospedale "M. Bufalini", Cesena, Italy.
Anselmo CampagnaAssessorato Cura Della Persona, Regione Emilia-Romagna, Salute e Walfare, Bologna, Italy.
Giovanni GordiniAnesthesia and Critical Care Ospedale, Ospedale Maggiore, Bologna, Italy.
Paolo NavalesiAnesthesia and Critical Care, Department of Medicine, DIMED - University of Padua, University Hospital of Padua, Padua, Italy.
Annalisa BoscoloAnesthesia and Critical Care, Department of Medicine, DIMED - University of Padua, University Hospital of Padua, Padua, Italy.
Alessandro GrazianoAnesthesia and Critical Care, Department of Medicine, DIMED - University of Padua, University Hospital of Padua, Padua, Italy.
Ilaria ValeriAnesthesia and Critical Care, Department of Medicine, DIMED - University of Padua, University Hospital of Padua, Padua, Italy.
Andrea VianelloRespiratory Pathophysiology Division University-City Hospital of Padua, Padua, Italy.
Danilo CeredaDirezione Generale Welfare, Lombardy Region, Milan, Italy.
Claudia FilippiniDipartimento Di Scienze Chirurgiche, Università Di Torino, Torino, Italy.
Maurizio CecconiDepartment of Anesthesia and Intensive Care, Humanitas Clinical and Research Center, Humanitas University, Milan, Italy.
Franco LocatelliDepartment of Pediatric Hematology and Oncology, Sapienza University of Rome, IRCCS Ospedale Pediatrico Bambino Gesù. President of the "Consiglio Superiore Di Sanità", Rome, Italy.
Michele BartolettiAlma Mater Studiorum, Dipartimento Di Scienze Mediche E Chirurgiche, Infectious Diseases Unit, Università Di Bologna, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Maddalena GiannellaAlma Mater Studiorum, Dipartimento Di Scienze Mediche E Chirurgiche, Infectious Diseases Unit, Università Di Bologna, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Pierluigi VialeAlma Mater Studiorum, Dipartimento Di Scienze Mediche E Chirurgiche, Infectious Diseases Unit, Università Di Bologna, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Massimo AntonelliDept. of Intensive Care Emergency Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Stefano NavaDepartment of Clinical, Integrated, and Experimental Medicine (DIMES), Respiratory and Critical Care, Sant'Orsola Malpighi Hospital, Bologna, Italy.
Antonio PesentiAlma Mater Studiorum, Dipartimento Di Scienze Mediche E Chirurgiche, Anesthesia and Intensive Care Medicine, Università Di Bologna, Policlinico Di Sant'Orsola, Via Massarenti, 9 40138, Bologna, Italy.
V Marco RanieriDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
COVID-19 Northern Italian ICU Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA Covid-19 outbreak developed in Lombardy, Veneto and Emilia-Romagna (Italy) at the end of February 2020. Fear of an imminent saturation of available ICU beds generated the notion that rationing of intensive care resources could have been necessary.

resultsIn order to evaluate the impact of Covid-19 on the ICU capacity to manage critically ill patients, we performed a retrospective analysis of the first 2 weeks of the outbreak (February 24-March 8). Data were collected from regional registries and from a case report form sent to participating sites. ICU beds increased from 1545 to 1989 (28.7%), and patients receiving respiratory support outside the ICU increased from 4 (0.6%) to 260 (37.0%). Patients receiving respiratory support outside the ICU were significantly older [65 vs. 77 years], had more cerebrovascular (5.8 vs. 13.1%) and renal (5.3 vs. 10.0%) comorbidities and less obesity (31.4 vs. 15.5%) than patients admitted to the ICU. PaO

conclusionsIncrease in ICU beds and use of out-of-ICU respiratory support allowed effective management of the first 14 days of the Covid-19 outbreak, avoiding resource rationing.

Indexed as

Acute respiratory failureCOVID-19ICUNon-invasive ventilationRationing

Identifiers

PMID33044646
PMCPMC7549086

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.