Evidence map›Paper›PMID 33044642›Full record

ReviewCurrent rheumatology reports2020

Treatment of Giant Cell Arteritis and Takayasu Arteritis-Current and Future.

B Hellmich, A F Águeda, S Monti, R Luqmani

Open access · bronzeAbstract readReview
In one paragraph

Review in Current rheumatology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Article
  9. Secondary Amyloidosis Treated with Tocilizumab as a Complication of Temporal Arteritis.European journal of case reports in internal medicine · 2024
    Article
  10. Review
  11. Article
  12. Observational
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  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

B HellmichKlinik für Innere Medizin, Rheumatologie und Immunologie, Vaskulitis-Zentrum Süd, Medius Kliniken, akademisches Lehrkrankenhaus der Universität Tübingen, Kirchheim-unter-Teck, Germany. b.hellmich@medius-kliniken.de.
A F ÁguedaDepartment of Rheumatology, Centro Hospitalar e Universitário da Cova da Beira, Covilhã, Portugal.
S MontiDepartment of Rheumatology, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy.
R LuqmaniNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Hospital Center of Cova da Beira · PTIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Oxford · GB

Funding

Medical Research Council MR/N011775/1
6 · The paper itself

Abstract

purpose of reviewGuidelines for the management of large vessel vasculitides have been recently updated by several scientific societies. We have evaluated the current recommendations for treatment of giant cell arteritis (GCA) and Takayasu arteritis (TA) and addressed potential future therapeutic strategies. RECENT

findingsWhile glucocorticoids (GCs) remain the gold standard for induction of remission, many patients relapse and acquire high cumulative GC exposure. Thus, GC-sparing therapies such as methotrexate are recommended for selected patients with GCA and all patients with TA. Recent high-quality evidence shows that tocilizumab is an effective GC-sparing agent in GCA. Non-biologic and biologic immunomodulators also appear to have GC-sparing properties in TA. Tocilizumab is now considered to be part of the standard treatment for GCA, particularly with relapsing disease, but questions on its use such as length of treatment and monitoring of disease activity remain open. High-quality evidence to guide treatment of TA is still lacking.

Indexed as

Giant Cell ArteritisTakayasu ArteritisAntibodies, Monoclonal, HumanizedGlucocorticoidsHumansMethotrexateRecurrenceAntibodies, Monoclonal, HumanizedGlucocorticoidsMethotrexatetocilizumabBiologicsGiant cell arteritisGlucocorticoidsLarge vessel vasculitisTakayasu arteritisTreatment

Identifiers

PMID33044642
PMCPMC7549425
OpenAlexW3092533456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.