Evidence map›Paper›PMID 33044637›Full record

ReviewClinical journal of gastroenterology2021

A rare case of metachronous neuroendocrine tumor after a colorectal adenocarcinoma: qualitative critical review of synchronous and metachronous gastrointestinal NET.

Francesco Lancellotti, Luigi Solinas, Davide Telesco, Andrea Sagnotta, Augusto Belardi, Giuseppina Balsamo, Stefano Mancini

Open access · hybridAbstract readCase ReportsReview
In one paragraph

Review in Clinical journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Francesco LancellottiDepartment of Surgical Sciences, Sapienza University of Rome, Rome, Italy. francesco.lancellotti87@gmail.com.ORCID http://orcid.org/0000-0002-1830-127X
Luigi SolinasDepartment of General Surgery and Surgical Oncology, San Filippo Neri Hospital, Rome, Italy.
Davide TelescoDepartment of General Surgery, Surgical Specialities "Paride Stefanini", Sapienza University of Rome, Rome, Italy.
Andrea SagnottaDepartment of General Surgery and Surgical Oncology, San Filippo Neri Hospital, Rome, Italy.
Augusto BelardiDepartment of General Surgery and Surgical Oncology, San Filippo Neri Hospital, Rome, Italy.
Giuseppina BalsamoDepartment of Clinical Pathology, San Filippo Neri Hospital, Rome, Italy.
Stefano ManciniDepartment of General Surgery and Surgical Oncology, San Filippo Neri Hospital, Rome, Italy.
Ospedale San Filippo Neri · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal neuroendocrine tumor (NET) associated with a metachronous intestinal adenocarcinoma is rare. We report the case of a 71-year-old man with an ileal NET. Patient has previously undergone a left colectomy for sigmoid cancer. We report a complete review both of the metachronous and synchronous NET. A comprehensive systematic literature search in PubMed, EMBASE, and MEDLINE identified a total of 35 relevant studies. This study includes an analysis of review articles, case reports, case series, retrospective studies and population-based studies. In the English literature to date, there are 21 case reports (19 synchronous cases and 2 metachronous cases), 3 case series and 3 review articles, and less than 10 retrospective studies or population-based studies. A total of 31 patients in 24 articles were included in the study: 28 patients with a synchronous gastrointestinal NET and colorectal adenocarcinoma and 3 patients with metachronous gastrointestinal NET and colorectal adenocarcinoma. The incidence of synchronous cancer (particularly for colorectal and gastric cancer) with a gastrointestinal NET ranges from 10 to 50%, while for the metachronous ones it is still unclear. This is the third metachronous case report and the first descriptive case of gastrointestinal NET diagnosed 2 years after a colorectal adenocarcinoma. An endoscopic follow-up program for gastrointestinal NET patients and/or for first-degree relatives of NET patients appears recommendable.

Indexed as

AdenocarcinomaColorectal NeoplasmsNeoplasms, Multiple PrimaryNeoplasms, Second PrimaryNeuroendocrine TumorsStomach NeoplasmsAgedHumansMaleRetrospective StudiesCoexisting tumorsColorectal adenocarcinomaGastrointestinal carcinoidsMetachronous neuroendocrineSynchronous NET

Identifiers

PMID33044637
PMCPMC7886727
OpenAlexW3092054916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.