Evidence map›Paper›PMID 33044462›Full record

ArticleJournal of visualized experiments : JoVE2020

Generating a Fractal Microstructure of Laminin-111 to Signal to Cells.

Camila Hochman-Mendez, Tatiana Coelho-Sampaio, Ariel J Kent, Jamie L Inman, Mina J Bissell, Claire Robertson

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camila Hochman-MendezRegenerative Medicine Research, Texas Heart Institute.
Tatiana Coelho-SampaioInstitute of Biomedical Sciences, Federal University of Rio de Janeiro.
Ariel J KentBiological Systems and Engineering, Lawrence Berkeley National Lab.
Jamie L InmanBiological Systems and Engineering, Lawrence Berkeley National Lab.
Mina J BissellBiological Systems and Engineering, Lawrence Berkeley National Lab.
Claire RobertsonMaterials Engineering Division, Lawrence Livermore National Lab; clairejanerobertson@gmail.com.

Funding

Definition of the Microenvironment in Breast CancerR01CA064786 · NCI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI BISSELL, MINA · 1995 to 2020
$6.1M
NCI NIH HHS R01 CA064786
6 · The paper itself

Abstract

Laminin-111 (Ln1) is an essential part of the extracellular matrix in epithelia, muscle and neural systems. We have previously demonstrated that the microstructure of Ln1 alters the way that it signals to cells, possibly because Ln1 assembly into networks exposes different adhesive domains. In this protocol, we describe three methods to generate polymerized Ln1.

Indexed as

Signal TransductionExtracellular MatrixFractalsLamininPolymerizationLaminin

Identifiers

PMID33044462
PMCPMC9394452

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.