ArticleJournal of Alzheimer's disease : JAD2020
Adherence to Dietary Patterns and Risk of Incident Dementia: Findings from the Atherosclerosis Risk in Communities Study.
Article in Journal of Alzheimer's disease : JAD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- The role of the Mediterranean diet in reducing the risk of cognitive impairement, dementia, and Alzheimer's disease: a meta-analysis.GeroScience · 2025Pooled it
- Dietary Intake, Mediterranean and Nordic Diet Adherence in Alzheimer's Disease and Dementia: A Systematic Review.Nutrients · 2025Pooled it
- Association between Mediterranean diet and dementia and Alzheimer disease: a systematic review with meta-analysis.Aging clinical and experimental research · 2024Pooled it
- Whole Dietary Patterns, Cognitive Decline and Cognitive Disorders: A Systematic Review of Prospective and Intervention Studies.Nutrients · 2023Pooled it
- Diet Quality and Dementia Risk in Older Adults With Alzheimer Pathology.JAMA network open · 2026Article
- Dietary Patterns and Indicators of Cognitive Function.JAMA neurology · 2026Article
- Evidence of an anti-inflammatory diet as a key protector for subjective memory complaints in women.BMC complementary medicine and therapies · 2025Article
- Impact of Diverse Dietary Patterns on Cognitive Health: Cumulative Evidence from Prospective Cohort Studies.Nutrients · 2025Review
- Dietary patterns and risk of Alzheimer's disease and related dementias across 5 racial and ethnic groups in the Multiethnic Cohort Study.The American journal of clinical nutrition · 2025Observational
- Dietary patterns identified by latent class analysis in relation to the risk of cardiovascular disease: Tehran lipid and glucose study.Journal of health, population, and nutrition · 2025Article
- Plant-Based Diets and Cardiovascular Events: A Proteomics Approach to Examine the Underlying Pathways.The Journal of nutrition · 2025Article
- Healthy Dietary Pattern Improves Cognitive Function in Elderly Persons With Periodontitis: A Cross-Sectional Study of NHANES.International dental journal · 2025Article
- Perspective on the health effects of unsaturated fatty acids and commonly consumed plant oils high in unsaturated fat.The British journal of nutrition · 2024Review
- Association between nutrition and cognition in a multi-ethnic cohort from Singapore.European journal of nutrition · 2023Article
- Dietary Patterns and Alzheimer's Disease: An Updated Review Linking Nutrition to Neuroscience.Nutrients · 2023Review
- Article
- Midlife omega-3 fatty acid intake predicts later life white matter microstructure in an age- and APOE-dependent manner.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Diet's Role in Modifying Risk of Alzheimer's Disease: History and Present Understanding.Journal of Alzheimer's disease : JAD · 2023Review
- Leveraging Observational Cohorts to Study Diet and Nutrition in Older Adults: Opportunities and Obstacles.Advances in nutrition (Bethesda, Md.) · 2022Review
- Dementia and Diet, Methodological and Statistical Issues: A Pilot Study.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPrevious studies have suggested that adherence to healthy dietary patterns during late life may be associated with improved cognition. However, few studies have examined the association between healthy dietary patterns during midlife and incident dementia.
objectiveOur study aimed to determine the association between adherence to healthy dietary patterns at midlife and incident dementia.
methodsWe included 13,630 adults from the Atherosclerosis Risk in Communities (ARIC) Study in our prospective analysis. We used food frequency questionnaire responses to calculate four dietary scores: Healthy Eating Index-2015 (HEI-2015), Alternative Healthy Eating Index-2010 (AHEI-2010), alternate Mediterranean (aMed) diet, and Dietary Approaches to Stop Hypertension (DASH). Participants were followed until the end of 2017 for incident dementia. Cox regression models adjusted for covariates were used to estimate risk of incident dementia by quintile of dietary scores.
resultsOver a median of 27 years, there were 2,352 cases of incident dementia documented. Compared with participants in quintile 1 of HEI-2015, participants in quintile 5 (healthiest) had a 14% lower risk of incident dementia (hazard ratio, HR: 0.86, 95% confidence interval, CI: 0.74-0.99). There were no significant associations of incident dementia with the AHEI-2010, aMed, or DASH scores. There were no significant interactions by sex, age, race, education, physical activity, hypertension, or obesity.
conclusionAdherence to the HEI-2015, but not the other dietary scores, during midlife was associated with lower risk of incident dementia. Further research is needed to elucidate whether timing of a healthy diet may influence dementia risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.