Evidence map›Paper›PMID 33044116›Full record

SynthesisThe Journal of international medical research2020

Telomerase reverse transcriptase rs2736098 polymorphism is associated with lung cancer: A meta-analysis.

Meihua Wang, Yaping Sun

Abstract readMeta-Analysis
In one paragraph

Synthesis in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Telomere length andRadiology and oncology · 2024
    Observational
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Meihua WangDepartment of Respiration, XiXi Hospital of Hangzhou, Hangzhou, China.
Yaping SunDepartment of Tuberculosis, Hangzhou Red Cross Hospital, Hangzhou, China.ORCID https://orcid.org/0000-0002-6454-0861

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA meta-analysis was conducted to determine whether telomerase reverse transcriptase (TERT) rs2736098 polymorphism was related to the incidence of lung cancer.

methodsWe systematically searched the following three electronic databases: PubMed, Embase, and China National Knowledge Infrastructure (CNKI), for relevant articles. Statistical analysis was performed using the odds ratio (OR) and the corresponding 95% confidence interval (CI).

resultsSeven articles involving 3836 healthy controls and 3637 patients were included in this meta-analysis.

conclusionThe present findings indicate that the

Indexed as

Lung NeoplasmsTelomeraseCase-Control StudiesChinaGenetic Predisposition to DiseaseHumansPolymorphism, Single NucleotideRisk FactorsTelomerasedominantHardy–Weinberg equilibriumlung cancerPolymorphismrecessivetelomerase reverse transcriptasetelomere

Identifiers

PMID33044116
PMCPMC7555572

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.