Evidence map›Paper›PMID 33043870›Full record

ArticlePathogens and global health2020

Cellular mechanisms regulating synthetic sex ratio distortion in the

Roya Elaine Haghighat-Khah, Atashi Sharma, Mariana Reis Wunderlich, Giulia Morselli, Louise Anna Marston, Christopher Bamikole, Ann Hall, Nace Kranjc, Chrysanthi Taxiarchi, Igor Sharakhov and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Pathogens and global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Roya Elaine Haghighat-KhahDepartment of Life Sciences, Imperial College London , London, UK.ORCID 0000-0002-9741-5282
Atashi SharmaDepartment of Entomology, Virginia Polytechnic Institute and State University , Blacksburg, VA, USA.
Mariana Reis WunderlichDepartment of Life Sciences, Imperial College London , London, UK.
Giulia MorselliDepartment of Life Sciences, Imperial College London , London, UK.
Louise Anna MarstonDepartment of Life Sciences, Imperial College London , London, UK.ORCID 0000-0002-8441-773X
Christopher BamikoleDepartment of Life Sciences, Imperial College London , London, UK.
Ann HallDepartment of Life Sciences, Imperial College London , London, UK.
Nace KranjcDepartment of Life Sciences, Imperial College London , London, UK.ORCID 0000-0001-7720-8430
Chrysanthi TaxiarchiDepartment of Life Sciences, Imperial College London , London, UK.ORCID 0000-0002-6616-5241
Igor SharakhovDepartment of Entomology, Virginia Polytechnic Institute and State University , Blacksburg, VA, USA.ORCID 0000-0003-0752-3747
Roberto GaliziDepartment of Life Sciences, Imperial College London , London, UK.ORCID 0000-0003-3134-7480
Imperial College London · GBNational Research Tomsk State University · RUVirginia Tech · US

Funding

Improving genome assemblies for species of the Anopheles gambiae complexR21AI135298 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SHARAKHOV, IGOR V · 2018 to 2019
$440k
NIAID NIH HHS R21 AI135298
6 · The paper itself

Abstract

Genetic control strategies aimed to bias the sex of progenies towards males present a promising new paradigm to eliminate malaria-transmitting mosquitoes. A synthetic sex-ratio distortion (SD) system was successfully engineered in

Indexed as

AnophelesGerm CellsSex ChromosomesSex RatioAnimalsFemaleMaleMeiosisend-joining repairFluorescence in situ hybridization (FISH); sex chromosomes; male-bias; transgenic.gene drivegenetic controlgeneticsmalariameiosismeiotic checkpointsmolecular mechanismsmosquitorDNASex ratio distortionY-drive

Identifiers

PMID33043870
PMCPMC7580827
OpenAlexW3092514193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.