Evidence map›Paper›PMID 33043786›Full record

ArticleSmall GTPases2021

Exploring a role for fatty acid synthase in prostate cancer cell migration.

Mario De Piano, Valeria Manuelli, Giorgia Zadra, Massimo Loda, Gordon Muir, Ash Chandra, Jonathan Morris, Mieke Van Hemelrijck, Claire M Wells

Open access · bronzeAbstract read
In one paragraph

Article in Small GTPases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mario De PianoSchool of Cancer and Pharmaceutical Sciences, Kings College London, London, UK.
Valeria ManuelliSchool of Cancer and Pharmaceutical Sciences, Kings College London, London, UK.
Giorgia ZadraDepartments of Oncologic Pathology and Pathology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Massimo LodaDepartments of Oncologic Pathology and Pathology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Gordon MuirUrology, King's College Hospital, London, UK.
Ash ChandraCellular Pathology, St. Thomas' Hospital, London, UK.
Jonathan MorrisSchool of Cancer and Pharmaceutical Sciences, Kings College London, London, UK.
Mieke Van HemelrijckSchool of Cancer and Pharmaceutical Sciences, Kings College London, London, UK.ORCID 0000-0002-7317-0858
Claire M WellsSchool of Cancer and Pharmaceutical Sciences, Kings College London, London, UK.
King's College London · GBBrigham and Women's Hospital · USKing's College Hospital · GBSt Thomas' Hospital · GB

Funding

Medical Research Council
6 · The paper itself

Abstract

Fatty acid synthase (FASN) is commonly overexpressed in prostate cancer and associated with tumour progression. FASN is responsible for

Indexed as

Cell MovementGene Expression Regulation, EnzymologicGene Expression Regulation, NeoplasticApoptosisBiomarkers, TumorCell ProliferationFatty Acid Synthase, Type IHepatocyte Growth FactorHumansMaleProstatic NeoplasmsTumor Cells, CulturedBiomarkers, TumorFASN protein, humanFatty Acid Synthase, Type IHepatocyte Growth FactorFatty acid synthaseprostate cancerRhoU

Identifiers

PMID33043786
PMCPMC8205051
OpenAlexW3092601292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.