Evidence map›Paper›PMID 33043414›Full record

ArticleJournal of autism and developmental disorders2021

Associations Between Limbic System White Matter Structure and Socio-Emotional Functioning in Children with ADHD + ASD.

Kate Stephens, Timothy J Silk, Vicki Anderson, Philip Hazell, Peter G Enticott, Emma Sciberras

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Article
  10. Cell Recognition Using BP Neural Network Edge Computing.Contrast media & molecular imaging · 2022
    Article
  11. The structural connectome in ADHD.Psychoradiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kate StephensSchool of Psychology, Deakin University, Geelong, VIC, Australia.ORCID http://orcid.org/0000-0003-4047-0173
Timothy J SilkSchool of Psychology, Deakin University, Geelong, VIC, Australia.
Vicki AndersonMurdoch Children's Research Institute, Parkville, Vic, Australia.
Philip HazellThe University of Sydney, Sydney, NSW, Australia.
Peter G EnticottSchool of Psychology, Deakin University, Geelong, VIC, Australia.
Emma SciberrasSchool of Psychology, Deakin University, Geelong, VIC, Australia. emma.sciberras@deakin.edu.au.

Funding

Australian National Health and Medical Research Council 1008522Australian National Health and Medical Research Council 1065895Australian National Health and Medical Research Council 1110688
6 · The paper itself

Abstract

Children with attention deficit/hyperactivity disorder (ADHD) combined with autism spectrum disorder (ASD) symptoms (ADHD + ASD) have poorer social and emotional functioning than those with ADHD alone. However, no studies have specifically examined the associations between ASD symptoms, measures of social and emotional functioning and limbic system white matter microstructure. Tractography on the cingulum, uncinate fasciculus and fornix were performed for 151 children with (N = 78) and without (N = 73) ADHD. Participants in the ADHD group who scored 11 or above on the Social Communication Questionnaire were classified as the ADHD + ASD group (N = 16). Significant differences in mean cingulum FA were present between the control group and the ADHD (all) group, however, no significant differences were seen between the ADHD and ADHD + ASD groups. Despite this, significant associations were seen between mean FA of the left cingulum and emotional problems for the ADHD + ASD group. Results give greater insights into the specific biological basis of emotional problems in the ADHD + ASD group, indicating that the cingulum may play a role.

Indexed as

Attention Deficit Disorder with HyperactivityAutism Spectrum DisorderEmotionsAdolescentChildComorbidityHumansLimbic SystemMaleNerve NetSurveys and QuestionnairesWhite MatterAttention deficit/hyperactivity disorderAutism spectrum disorderBrain imagingComorbidity

Identifiers

PMID33043414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.