Evidence map›Paper›PMID 33043305›Full record

ArticleSTAR protocols2020

Generation of Human Neutrophils from Induced Pluripotent Stem Cells in Chemically Defined Conditions Using

Aditi Majumder, Kran Suknuntha, David Bennin, Lucas Klemm, Vera S Brok-Volchanskaya, Anna Huttenlocher, Igor Slukvin

Open access · goldAbstract read
In one paragraph

Article in STAR protocols, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. CAR-engineered neutrophils derived from induced pluripotent stem cells: a new frontier in cellular immunotherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Review
  3. Decoding Pain: Next-Generation In Vitro Systems for Mechanistic Insights and Drug Discovery.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Sourcing cells forFrontiers in medical technology · 2022
    Review
  12. Roles of mitochondria in neutrophils.Frontiers in immunology · 2022
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Aditi MajumderWisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA.
Kran SuknunthaWisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA.
David BenninChakri Naruebodindra Medical Institute, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Samut Prakan 10540, Thailand.
Lucas KlemmDepartment of Pediatrics and Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Vera S Brok-VolchanskayaWisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA.
Anna HuttenlocherDepartment of Pediatrics and Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Igor SlukvinWisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA.
University of Wisconsin–Madison · USMahidol University · TH

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Training Program In Molecular AND Cellular PharmacologyT32GM008688 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI AUDHYA, ANJON · 1998 to 2020
$6.0M
Microscale models of inflammation and its resolutionR01AI134749 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI BEEBE, DAVID J, HUTTENLOCHER, ANNA · 2018 to 2022
$3.8M
Molecular Determinants of Hemogenic EndotheliumR01HL142665 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI SLUKVIN, IGOR I. · 2018 to 2021
$2.0M
NHLBI NIH HHS R01 HL142665NIAID NIH HHS R01 AI134749NIGMS NIH HHS T32 GM008688NIH HHS P51 OD011106
6 · The paper itself

Abstract

This protocol describes a rapid and efficient feeder-, serum-, and xeno-free method for neutrophil generation from hiPSCs using

Indexed as

Cell Culture TechniquesCell DifferentiationCells, CulturedHumansInduced Pluripotent Stem CellsNeutrophilsRNA, MessengerTranscription FactorsETV2 protein, humanRNA, MessengerTranscription Factors

Identifiers

PMID33043305
PMCPMC7543976
OpenAlexW3045584192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.