ArticleERJ open research2020
Blood eosinophil level and lung function trajectories: cross-sectional and longitudinal studies in European cohorts.
Article in ERJ open research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- The Inflammation-Metabolism Axis in Preserved Ratio Impaired Spirometry: Pathogenic Mechanisms and Translational Implications.Journal of inflammation research · 2026Review
- Association of Blood Eosinophil Counts with Expiratory Airflow Limitation: A Multi-Ethnicity Observational Study.Journal of inflammation research · 2026Article
- The association between systemic inflammation, lung function and respiratory symptoms in the BOLD study in Northern Europe.Scientific reports · 2025Article
- Eosinophil-Derived Neurotoxin Determinants and Reference Values in a Swedish Middle-Aged General Population.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025Article
- Severe Dry Cough Followed by Eosinophilia Without Pulmonary Infiltrates After Dupilumab Treatment in Patients with Severe Asthma: A Series of Five Cases.Journal of inflammation research · 2025Article
- Lung function trajectories in a cohort of patients with moderate-to-severe asthma on mepolizumab, omalizumab, or dupilumab.Allergy · 2024Article
- Elevated Proportions of Circulating CXCR5Journal of immunology research · 2024Article
- Article
- House Dust Mite Subcutaneous Immunotherapy and Lung Function Trajectory in Children and Adolescents with Asthma.Children (Basel, Switzerland) · 2022Article
- Uncontrolled asthma from childhood to young adulthood associates with airflow obstruction.ERJ open research · 2021Article
- The influence of individual characteristics and non-respiratory diseases on blood eosinophil count.Clinical and translational allergy · 2021Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundElevated blood eosinophils have been associated with lower lung function and are believed to be associated with accelerated lung function decline.
methodBlood eosinophils were measured in four cohorts: <45 years cohort within the Vlagtwedde-Vlaardingen (V&V) study, the Uppsala cohort of the European Community Respiratory Health Survey (ECRHS-Uppsala; <45 years), ≥45 years cohort within the V&V study, and the Rotterdam study (≥45 years). Blood eosinophils at baseline were classified as normal (<300 cells·μL
resultsElevated blood eosinophils were associated with lower FEV
conclusionElevated blood eosinophils are associated with lower lung function in the general population and with an accelerated lung function decline among asthmatic individuals.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.