Evidence map›Paper›PMID 33042863›Full record

ArticleFrontiers in cellular and infection microbiology2020

Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to

Chao Wu, Mengzhen Yang, Rui Liu, Hanyang Hu, Lulu Ji, Xiaoli Zhang, Shenghe Huang, Lin Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Chao WuDepartment of Histology and Embryology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Mengzhen YangDepartment of Histology and Embryology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Rui LiuDepartment of Histology and Embryology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Hanyang HuDepartment of Histology and Embryology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Lulu JiDepartment of Histology and Embryology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Xiaoli ZhangDepartment of Ultrasound Imaging, Zhongnan Hospital of Wuhan University, Wuhan, China.
Shenghe HuangKunming Key Laboratory of Children Infection and Immunity, Yunnan Institute of Pediatrics, Kunming Children's Hospital, Kunming, China.
Lin WangDepartment of Histology and Embryology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Wuhan University · CNHubei Provincial Center for Disease Control and Prevention · CNKunming Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have shown that exposure to environmental tobacco smoke can increase the risk of bacterial meningitis, and nicotine is the core component of environmental tobacco smoke. Autophagy is an important way for host cells to eliminate invasive pathogens and resist infection.

Indexed as

Escherichia coliNicotineAutophagyBrainCells, CulturedEndothelial CellsHumansInfant, NewbornPhosphatidylinositol 3-KinasesNicotinePhosphatidylinositol 3-KinasesautophagyEscherichia colihuman brain microvascular endothelial cellsneonatal meningitisnicotine

Identifiers

PMID33042863
PMCPMC7522313
OpenAlexW3085605315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.