Evidence map›Paper›PMID 33042697›Full record

ArticleCureus2020

Induction of Combination Therapy for the Management of Hepatitis C: An Observational Study.

Sultan Z Khan, Muhammad Umar Talha, Bushra Iftikhar, Amina Noor, Talha Laique, Aamna Latif, Jahanzeb Malik

Abstract read
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sultan Z KhanGastroenterology, Abbottabad International Medical College, Abbottabad, PAK.
Muhammad Umar TalhaInternal Medicine, District Headquarter Hospital, Gujranwala, PAK.
Bushra IftikharBiochemistry, Azra Nadeed Medical College, Lahore, PAK.
Amina NoorInternal Medicine, Abbottabad International Medical College, Abbottabad, PAK.
Talha LaiquePharmacology, Lahore Medical and Dental College, Lahore, PAK.
Aamna LatifHematology, Ahmed Medical Complex, Rawalpindi, PAK.
Jahanzeb MalikCardiology, Rawalpindi Institute of Cardiology, Rawalpindi, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective Hepatitis C infection is prevalent in Pakistan. The purpose of this study was to observe the therapeutic effects of conventional interferon in combination with ribavirin among treatment-naive hepatitis C patients. Methods This descriptive cross-sectional study of hepatitis C combination therapy was conducted at our institute after approval. All the patients received treatment with conventional interferon (5-MU three times weekly) and ribavirin (1000mg/day) for four weeks. A follow-up for the rapid virological response (RVR) was done in the fourth week of treatment.  Results The mean age of the patients was 37.43. There was a gradual decrease in RVR with increasing age after four weeks of treatment.  Conclusion The combination therapy showed good RVR in the fourth week among all hepatitis C patients.

Indexed as

hepatitis cinterferonrapid virological responseribavirin

Identifiers

PMID33042697
PMCPMC7536117

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.