Evidence map›Paper›PMID 33042630›Full record

ArticleAmerican journal of cancer research2020

Endoscopic submucosal dissection versus esophagectomy for early esophageal squamous cell carcinoma with tumor invasion to different depths.

Wei An, Mu-Yun Liu, Jing Zhang, Yue-Ping Cui, Jie Gao, Li-Peng Wang, Ying Chen, Li-Xin Yang, He-Zhong Chen, Hai Jin and 6 more

Registry-linked trialAbstract read
In one paragraph

Article in American journal of cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06060106 (Endoscopic Submucosal Dissection Versus Esophagectomy for Early Esophageal Carcinoma:a Cohort Study), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06060106 completednot on this map

Endoscopic Submucosal Dissection Versus Esophagectomy for Early Esophageal Carcinoma:a Cohort Study

TypeobservationalSponsorChanghai HospitalRan2011 to 2023Enrolled191ConditionsEsophageal CancerArmsEndoscopic submucosal dissection, Esophagectomy
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Endoscopic resection versus esophagectomy for T1bN0M0 esophageal cancer: a systematic review and meta-analysis.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Esophageal ESD Training; Perspective of West vs. East.Current gastroenterology reports · 2025
    Review
  5. Article
  6. Article
  7. Characteristics of Esophageal Squamous Cell Carcinomas Based on Circumferential Localization.JGH open : an open access journal of gastroenterology and hepatology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Endoscopic submucosal dissectionTherapeutic advances in gastroenterology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Wei AnDepartment of Gastroenterology, Changhai Hospital of Second Military Medical University Shanghai, China.
Mu-Yun LiuDepartment of Gastroenterology, Changhai Hospital of Second Military Medical University Shanghai, China.
Jing ZhangDepartment of Pathology, Changhai Hospital of Second Military Medical University Shanghai, China.
Yue-Ping CuiDepartment of Gastroenterology, Navy 905 Hospital of Second Military Medical University Shanghai, China.
Jie GaoDepartment of Gastroenterology, Changhai Hospital of Second Military Medical University Shanghai, China.
Li-Peng WangInformation Centre, Changhai Hospital of Second Military Medical University Shanghai, China.
Ying ChenDepartment of Pathology, Changhai Hospital of Second Military Medical University Shanghai, China.
Li-Xin YangThoracic Surgery, Changhai Hospital of Second Military Medical University Shanghai, China.
He-Zhong ChenThoracic Surgery, Changhai Hospital of Second Military Medical University Shanghai, China.
Hai JinThoracic Surgery, Changhai Hospital of Second Military Medical University Shanghai, China.
Feng LiuGastrointestinal Endoscopy Center, The Tenth People's Hospital of Tongji University Shanghai, China.
Jie ChenDepartment of Gastroenterology, Changhai Hospital of Second Military Medical University Shanghai, China.
Zhao-Shen LiDepartment of Gastroenterology, Changhai Hospital of Second Military Medical University Shanghai, China.
Luo-Wei WangDepartment of Gastroenterology, Changhai Hospital of Second Military Medical University Shanghai, China.
Xin-Gang ShiDepartment of Gastroenterology, Changhai Hospital of Second Military Medical University Shanghai, China.
Chang SunDepartment of Gastroenterology, Changhai Hospital of Second Military Medical University Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic submucosal dissection (ESD) is a minimally invasive alternative to esophagectomy for early esophageal squamous cell carcinoma (EESCC). The aim of this study was to compare the efficacy and safety of ESD and esophagectomy in EESCC with different depth of invasion. The data of EESCC patients who received ESD or esophagectomy between Jan 2011 to Dec 2018 at our center were retrospectively analyzed. Overall survival (OS), disease-specific survival (DSS), recurrence-free survival (RFS), and procedure-related variables were compared between ESD and esophagectomy patients. 222 EESCC patients underwent ESD, while 184 underwent esophagectomy. No significant differences were found between the two groups in OS (

Indexed as

early esophageal squamous cell carcinomaESDesophagectomy

Identifiers

PMID33042630
PMCPMC7539777

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.