Evidence map›Paper›PMID 33042519›Full record

ReviewF1000Research2020

Endothelial nitric oxide synthase-derived nitric oxide in the regulation of metabolism.

Margarita Tenopoulou, Paschalis-Thomas Doulias

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 57 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Observational
  5. Review
  6. Review
  7. Article
  8. Review
  9. Effects of Nitric Oxide Expression on Hearing Loss.International journal of molecular sciences · 2025
    Review
  10. Article
  11. Serum heat shock protein 90 alpha levels in mild and severe preeclampsia.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  12. Article
  13. Complete autonomic blockade reveals nitric oxide contribution to blood pressure regulation in obese Black women.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. The rs2682826 Polymorphism of theLife (Basel, Switzerland) · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Margarita TenopoulouChildren's Hospital of Philadelphia Research Institute, 3517 Civic Center Boulevard, Philadelphia, Pennsylvania, 19104-4318, USA.
Paschalis-Thomas DouliasChildren's Hospital of Philadelphia Research Institute, 3517 Civic Center Boulevard, Philadelphia, Pennsylvania, 19104-4318, USA.ORCID 0000-0001-7891-3131
Children's Hospital of Philadelphia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitric oxide is an endogenously formed gas that acts as a signaling molecule in the human body. The signaling functions of nitric oxide are accomplished through two primer mechanisms: cGMP-mediated phosphorylation and the formation of S-nitrosocysteine on proteins. This review presents and discusses previous and more recent findings documenting that nitric oxide signaling regulates metabolic activity. These discussions primarily focus on endothelial nitric oxide synthase (eNOS) as the source of nitric oxide.

Indexed as

Signal TransductionHumansNitric OxideNitric Oxide Synthase Type IIINitric OxideNitric Oxide Synthase Type IIINOS3 protein, humanendothelial nitric oxide synthasemetabolismnitric oxidenitric oxide signalingprotein S-nitrosylation

Identifiers

PMID33042519
PMCPMC7531049
OpenAlexW3090858925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.