Evidence map›Paper›PMID 33042360›Full record

ReviewThe World Allergy Organization journal2020

Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD).

Philip W Rouadi, Samar A Idriss, Robert M Naclerio, David B Peden, Ignacio J Ansotegui, Giorgio Walter Canonica, Sandra Nora Gonzalez-Diaz, Nelson A Rosario Filho, Juan Carlos Ivancevich, Peter W Hellings and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in The World Allergy Organization journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Effects of PMToxics · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Air Pollution: Possible Interaction between the Immune and Nervous System?International journal of environmental research and public health · 2022
    Review
  17. Lockdown Amid COVID-19 Ascendancy over Ambient Particulate Matter Pollution Anomaly.International journal of environmental research and public health · 2022
    Review
  18. Review
  19. Review
  20. SH-29 and SK-119 Attenuates Air-Pollution Induced Damage by Activating Nrf2 in HaCaT Cells.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 11 countries.

Philip W RouadiDepartment of Otolaryngology-Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon.
Samar A IdrissDepartment of Otolaryngology-Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon.
Robert M NaclerioJohns Hopkins University Department of Otolaryngology - Head and Neck Surgery, Baltimore, MD, USA.
David B PedenUNC Center for Environmental Medicine, Asthma, and Lung Biology, Division of Allergy, Immunology and Rheumatology, Department of Pediatrics UNS School of Medicine, USA.
Ignacio J AnsoteguiDepartment of Allergy and Immunology, Hospital Quironsalud Bizkaia, Bilbao, Spain.
Giorgio Walter CanonicaAsthma & Allergy Clinic,Humanitas University & Research Hospital IRCCS, Milano, Italy.
Sandra Nora Gonzalez-DiazUniversity Autonoma de Nuevo Leon Facultad de Medicina y Hospital Universitario U.A.N.L, Monterrey, NL, c.p. 64460, México.
Nelson A Rosario FilhoFederal University of Parana, Brazil.
Juan Carlos IvancevichFaculty of Medicine, Universidad del Salvador, Buenos Aires, Argentina and Head of Allergy and Immunology at the Santa Isabel Clinic, Buenos Aires, Argentina.
Peter W HellingsDepartment of Otorhinolaryngology, University Hospitals Leuven, Leuven, Belgium.
Margarita Murrieta-Aguttes8 Rue Pierre Poli, Issy Les Moulineaux, 92130, France.
Fares H ZaitounLAUMC Rizk Hospital, Otolaryngology-Allergy Department, Beirut, Lebanon.
Carla IraniDepartment of Internal Medicine and Infectious Diseases, St Joseph University, Hotel Dieu de France Hospital, Beirut, Lebanon.
Marilyn R KaramDivision of Rheumatology, Allergy and Clinical Immunology, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.
Jean BousquetINSERM U 1168, VIMA: Ageing and Chronic Diseases Epidemiological and Public Health Approaches, Villejuif, France.
Rafik Hariri University Hospital · LBAmerican University of Beirut · LBAmsterdam UMC Location University of Amsterdam · NLHospital Quirónsalud Barcelona · ESHumanitas University · ITInserm · FRJohns Hopkins University · USSaint Joseph University · LBUniversidad Autónoma de Nuevo León · MXUniversidad del Salvador · ARUniversidade Federal do Paraná · BRUniversity Medical Center Rizk Hospital · LB

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Air pollution causes significant morbidity and mortality in patients with inflammatory airway diseases (IAD) such as allergic rhinitis (AR), chronic rhinosinusitis (CRS), asthma, and chronic obstructive pulmonary disease (COPD). Oxidative stress in patients with IAD can induce eosinophilic inflammation in the airways, augment atopic allergic sensitization, and increase susceptibility to infection. We reviewed emerging data depicting the involvement of oxidative stress in IAD patients. We evaluated biomarkers, outcome measures and immunopathological alterations across the airway mucosal barrier following exposure, particularly when accentuated by an infectious insult.

Indexed as

Air pollutionAntioxidantAR, Allergic rhinitisCOPD, Chronic obstructive pulmonary diseaseCRS, Chronic rhinosinusitisDEP, Diesel exhaust particlesIAD, Inflammatory airway diseasesILC, Innate lymphoid cellsIL, InterleukinInflammatory airway diseaseNOx, Nitrogen oxidesOxidative stress biomarkersPAH, Polycyclic aromatic hydrocarbonsPM, Particulate matterROS, Reactive oxygen speciesTBS, Tobacco smokeTLR, Toll-like receptorsTobacco smokeTreg, Regulatory T cellVOCs, Volatile organic compounds

Identifiers

PMID33042360
PMCPMC7534666
OpenAlexW3090733541

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.