Evidence map›Paper›PMID 33042331›Full record

ArticleInternational journal of clinical and experimental pathology2020

microRNA-133b represses the progression of lung cancer through inhibiting SOX9/β-catenin signaling pathway.

Shubin Liu, Shasha Li, Xiaoqiang Yu, Qiping Wang, Hui Sun

Abstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Analysis ofHeliyon · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shubin LiuDepartment of Oncology, Ganzhou Peoples Hospital Ganzhou 341000, Jiangxi, China.
Shasha LiDepartment of Respiratory Medicine, Ganzhou Peoples Hospital Ganzhou 341000, Jiangxi, China.
Xiaoqiang YuDepartment of Thoracic Surgery, Ruijin Peoples Hospital Ganzhou 342500, Jiangxi, China.
Qiping WangThe Three Department of Medicine, Dayu County Peoples Hospital Ganzhou 341500, Jiangxi, China.
Hui SunDepartment of Cardiothoracic Surgery, Ganzhou Peoples Hospital Ganzhou 341000, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNA-133b (miR-133b) has been shown to be down-regulated in lung cancer and functions as a tumor repressor. However, the underlying mechanisms of miR-133b in lung cancer are not clear. SOX9, a member of SOX family, serves as an oncogene in lung cancer by activating b-catenin signaling and was identified to be a direct target of miR-133b in breast cancer. Based on these data, the current study was performed to explore whether SOX9/b-catenin signaling is implicated in miR-133b-meditaed lung cancer repression. MiR-133b expression in lung cancer tissues and cells were detected by RT-PCR. CCK-8, colony formation, flow cytometry, transwell chamber and

Indexed as

lung cancerMiR-133bSOX9β-catenin

Identifiers

PMID33042331
PMCPMC7539883

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.