Evidence map›Paper›PMID 33042270›Full record

ArticleTheranostics2020

CSRP2 suppresses colorectal cancer progression

Lixia Chen, Xiaoli Long, Shiyu Duan, Xunhua Liu, Jianxiong Chen, Jiawen Lan, Xuming Liu, Wenqing Huang, Jian Geng, Jun Zhou

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. CSRP2 modulates PDGFRA/PI3K/AKT signaling via PRC1 components in glioma.Cellular oncology (Dordrecht, Netherlands) · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Effects of NaCell biochemistry and biophysics · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. [Role and mechanism of cysteine and glycine-rich protein 2 in the malignant progression of neuroblastoma].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lixia ChenDepartment of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Xiaoli LongDepartment of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Shiyu DuanDepartment of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Xunhua LiuDepartment of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jianxiong ChenDepartment of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jiawen LanDepartment of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Xuming LiuDepartment of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Wenqing HuangDepartment of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Jian GengDepartment of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jun ZhouDepartment of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Southern Medical University · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastasis is a major cause of death in patients with colorectal cancer (CRC). Cysteine-rich protein 2 (CSRP2) has been recently implicated in the progression and metastasis of a variety of cancers. However, the biological functions and underlying mechanisms of CSRP2 in the regulation of CRC progression are largely unknown.

Indexed as

AminoquinolinesAnimalsBiomarkers, TumorCarcinogenesisCell Line, TumorCell MovementCell ProliferationColonColorectal NeoplasmsCrk-Associated Substrate ProteinDisease ProgressionDown-RegulationEpithelial-Mesenchymal TransitionExtracellular Signal-Regulated MAP KinasesFemaleGene Expression Regulation, NeoplasticAminoquinolinesBCAR1 protein, humanBiomarkers, TumorCrk-Associated Substrate ProteinCSRP2 protein, humanExtracellular Signal-Regulated MAP KinasesLIM Domain ProteinsMuscle ProteinsNSC 23766Nuclear Proteinsp21-Activated KinasesProtein Serine-Threonine KinasesPyrimidinesrac1 GTP-Binding ProteinRAC1 protein, humanColorectal cancerCSRP2ERKHippoPAK

Identifiers

PMID33042270
PMCPMC7532686
OpenAlexW3084353241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.