Evidence map›Paper›PMID 33042264›Full record

ArticleTheranostics2020

Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma.

Saravana Kumar Kailasam Mani, Bingyu Yan, Zhibin Cui, Jiazeng Sun, Sagar Utturkar, Adrien Foca, Nadim Fares, David Durantel, Nadia Lanman, Philippe Merle and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 47 citations in OpenAlex.

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  4. Increased PRP19 in Hepatocyte Impedes B Cell Function to Promote Hepatocarcinogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Saravana Kumar Kailasam ManiDepartment of Basic Medical Sciences.
Bingyu YanDepartment of Biochemistry.
Zhibin CuiDepartment of Basic Medical Sciences.
Jiazeng SunDepartment of Basic Medical Sciences.
Sagar UtturkarPurdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907.
Adrien FocaCancer Research Center of Lyon UMR Inserm 1052 - CNRS 5286.
Nadim FaresDepartment of Hepatology, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Université Lyon 1, Lyon, France.
David DurantelCancer Research Center of Lyon UMR Inserm 1052 - CNRS 5286.
Nadia LanmanPurdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907.
Philippe MerleDepartment of Hepatology, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Université Lyon 1, Lyon, France.
Majid KazemianDepartment of Biochemistry.
Ourania AndrisaniDepartment of Basic Medical Sciences.
Center for Cancer Research · USPurdue University West Lafayette · USHôpital de la Croix-Rousse · FRHospices Civils de Lyon · FR

Funding

Role of CREB/ATF Proteins in Hepatocyte Growth ControlR01DK044533 · NIDDK · PURDUE UNIVERSITY WEST LAFAYETTE · PI ANDRISANI, OURANIA M. · 1999 to 2021
$5.1M
Expression, regulation, and role of enhancer RNAs in T helper cellsK22HL125593 · NHLBI · PURDUE UNIVERSITY · PI KAZEMIAN, MAJID · 2017 to 2019
$747k
NHLBI NIH HHS K22 HL125593NIDDK NIH HHS R01 DK044533
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntagomirsCarcinoma, HepatocellularCell Line, TumorDEAD-box RNA HelicasesDown-RegulationGene Expression Regulation, NeoplasticGene Knockdown TechniquesHepatitis B, ChronicHepatitis B virusHepatocytesHumansLiverLiver NeoplasmsMicroRNAsRNA, Long NoncodingRNA-SeqAntagomirsDdx5 protein, humanDEAD-box RNA HelicasesMicroRNAsMIR17HG, humanMIRN106 microRNA, humanRNA, Long NoncodingHepatitis B virusHepatocellular CarcinomamiR17~92/miR106b~25 & antagomirsRNA helicase DDX5Wnt/β-catenin signaling.

Identifiers

PMID33042264
PMCPMC7532671
OpenAlexW3083963129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.