ReviewFrontiers in immunology2020
Impact of Gallic Acid on Gut Health: Focus on the Gut Microbiome, Immune Response, and Mechanisms of Action.
Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
100 citing papers in PubMed, 1 synthesis or guideline pooled it, 216 citations in OpenAlex.
- Coffee by-products as the source of antioxidants: a systematic review.F1000Research · 2022Pooled it
- Dual Mechanistic Role of Polyphenols in Modulating the Insulin-Related Metabolic Pathways: Insights from Computer-Aided Analysis.Cell biochemistry and biophysics · 2026Article
- Review
- Niosomal Gallic Acid Attenuates Obesity-related Hepatic Steatosis Through Oxidative and Inflammatory Regulation With Associated Autophagy and Hedgehog Pathway Modulation.Applied biochemistry and biotechnology · 2026Article
- Effect of Methyl Gallate on Physiological and Gut Microbiota-Associated Responses Following a Single Intramuscular Administration of Tylosin in Weaned Piglets.Pathogens (Basel, Switzerland) · 2026Article
- Dietary gallic acid supplementation alleviates LPS-induced inflammatory responses and intestinal barrier damage in chickens at an early age.Poultry science · 2026Article
- 3D-Printed Alginate Dialdehyde (ADA)-Gelatin (GEL) Hydrogels with Gallic Acid (GA) for Enhanced Multifunctional Properties.ACS omega · 2026Article
- Beyond Antioxidants: The Microbial Metabolic Landscape of Anthocyanins and Their Downstream Health Implications.Nutrients · 2026Review
- Dietary gallic acid facilitate growth performance, improve slaughter performance through enhanced intestinal function in yellow-feathered broiler.Scientific reports · 2026Article
- Gallic acid antagonizes deoxynivalenol toxicity by inhibiting DON-induced ferroptosis.NPJ science of food · 2026Article
- Coarse-grained molecular dynamics simulation of gallic acid delivery using span60-based niosomes.Scientific reports · 2026Article
- Therapeutic Effects of Gallic Acid and Alpha-Tocopherol on Adenine-Induced Chronic Kidney Disease in Male Wistar Rats.Biochemistry research international · 2026Article
- Gallic acid improves the bactericidal efficacy of tylosin againstOpen veterinary journal · 2026Article
- Gallic Acid: A Potent Antioxidant and Anti-inflammatory Agent in Modern Cosmeceuticals.Recent advances in drug delivery and formulation · 2026Review
- Effects of Gallic Acid Supplementation on Intestinal Function and Gut Microbial Community Structure inAquaculture nutrition · 2026Article
- Effects of Glucose Oxidase andMetabolites · 2025Article
- Epigallocatechin Gallate as a Molecular Therapeutic in Heart Failure and Cardio-Oncology: Mechanistic Pathways and Translational Perspectives.International journal of molecular sciences · 2025Review
- Innovative Use of Gallic Acid as a Crosslinking Agent for Gelatin: A Biocompatible Strategy for 3D-Printed Scaffolds in Tissue Engineering.Pharmaceutics · 2025Article
- Article
- Selected Medicinal Plants Used in the Treatment and Management of Tuberculosis and Related Symptoms in South Africa.Pharmaceuticals (Basel, Switzerland) · 2025Review
40 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gallic acid (GA) is a naturally occurring polyphenol compound present in fruits, vegetables, and herbal medicines. According to previous studies, GA has many biological properties, including antioxidant, anticancer, anti-inflammatory, and antimicrobial properties. GA and its derivatives have multiple industrial uses, such as food supplements or additives. Additionally, recent studies have shown that GA and its derivatives not only enhance gut microbiome (GM) activities, but also modulate immune responses. Thus, GA has great potential to facilitate natural defense against microbial infections and modulate the immune response. However, the exact mechanisms of GA acts on the GM and immune system remain unclear. In this review, first the physicochemical properties, bioavailability, absorption, and metabolism of GA are introduced, and then we summarize recent findings concerning its roles in gastrointestinal health. Furthermore, the present review attempts to explain how GA influences the GM and modulates the immune response to maintain intestinal health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.